| Varkaris, Andreas; Pazolli, Ermira; Gunaydin, Hakan; Wang, Qi; Pierce, Levi et al. (2023). Discovery and clinical proof-of-concept of RLY-2608, a first-in-class mutant-selective allosteric PI3Ka inhibitor that decouples anti-tumor activity from hyperinsulinemia. Cancer Discovery . 10.1158/2159-8290.cd-23-0944. [PDB: 8ts7] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Frota, N.F.; Pistofidis, A.; Folger, I.B.; Hilvert, D.; Schmeing, T.M. et al. (2023). The condensation domain of surfactin A synthetase C in space group P212121. Protein Data Bank: 8f7g. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Frota, N.; Pistofidis, A.; Folger, I.B.; Hilvert, D.; Schmeing, T.M. et al. (2023). The condensation domain of surfactin A synthetase C in space group P43212. Protein Data Bank: 8f7f. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Wang, F.; Cheng, W.; Yuan, Z.; Lin, D.; Guo, S. et al. (2023). The Crystal Structure of Mms2 from Biortus. Protein Data Bank: 8wr5. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Palte, R.L. (2023). Structure of Compound 13 bound to the CHK1 10-point mutant. Protein Data Bank: 8six. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Kattar, Solomon D.; Gulati, Anmol; Margrey, Kaila A.; Keylor, Mitchell H.; Ardolino, Michael et al. (2023). Discovery of MK-1468: A Potent, Kinome-Selective, Brain-Penetrant Amidoisoquinoline LRRK2 Inhibitor for the Potential Treatment of Parkinson’s Disease. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.3c01486. [PDB: 8six] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Kang, R.W.; Thai, E.; Julien, J.P. (2023). Crystal structure of Ky15.11-S100IK Fab in complex with circumsporozoite protein KQPA peptide. Protein Data Bank: 8fb5. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Thai, Elaine; Murugan, Rajagopal; Binter, Špela; Burn Aschner, Clare; Prieto, Katherine et al. (2023). Molecular determinants of cross-reactivity and potency by VH3-33 antibodies against the Plasmodium falciparum circumsporozoite protein. Cell Reports 42(11) , 113330. 10.1016/j.celrep.2023.113330. [PDB: 8fb5] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Kozlov, G.; Gehring, K. (2023). LaM domain of human LARP1 in complex with AAAAGA RNA. Protein Data Bank: 8ey8. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Kozlov, G.; Gehring, K. (2023). LaM domain of human LARP1 in complex with AAAGAA RNA. Protein Data Bank: 8ey7. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Kozlov, G.; Gehring, K. (2023). LaM domain of human LARP1 in complex with AAAAAG RNA. Protein Data Bank: 8ey6. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Kariolis, M.S.; Lexa, K.; Liau, N.P.D.; Srivastava, D.; Tran, H. et al. (2023). Structure of complex between TV6.6 and CD98hc ECD. Protein Data Bank: 8g0m. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Chew, Kylie S.; Wells, Robert C.; Moshkforoush, Arash; Chan, Darren; Lechtenberg, Kendra J. et al. (2023). CD98hc is a target for brain delivery of biotherapeutics. Nature Communications 14(1) . 10.1038/s41467-023-40681-4. [PDB: 8g0m] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Gui, W.; Wang, F.; Cheng, W.; Gao, J.; Huang, Y. et al. (2023). The Crystal Structure of CDK3 and CyclinE1 Complex with Dinaciclib from Biortus. Protein Data Bank: 8h4r. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Wang, F.; Cheng, W.; Yuan, Z.; Qi, J.; Li, J. et al. (2023). The Crystal Structure of integrase from Biortus. Protein Data Bank: 8wf7. |
CMCF-ID |
PDB Deposition |
Health |