| Szabla, Robert; Li, Mingyi; Warner, Victoria; Song, Yifeng; Junop, Murray et al. (2024). DdrC, a unique DNA repair factor from D. radiodurans, senses and stabilizes DNA breaks through a novel lesion-recognition mechanism. Nucleic Acids Research 52(15) , 9282-9302. 10.1093/nar/gkae635. |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Dolgova, Natalia; Uhlemann, Eva-Maria E; Boniecki, Michal T; Vizeacoumar, Frederick S; Ara, Anjuman et al. (2024). MEMO1 binds iron and modulates iron homeostasis in cancer cells. eLife 13. 10.7554/elife.86354. |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Naineni, Sai Kiran; Bhatt, Garvit; Jiramongkolsiri, Ekkanat; Robert, Francis; Cencic, Regina et al. (2024). Protein–RNA interactions mediated by silvestrol—insight into a unique molecular clamp. Nucleic Acids Research 52(20) , 12701-12711. 10.1093/nar/gkae824. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Kozlov, Guennadi; Jiang, Jianning; Rutherford, Tyler; Noronha, Anne M.; Wilds, Christopher J. et al. (2024). Enhanced binding of guanylated poly(A) RNA by the LaM domain of LARP1. RNA Biology 21(1) , 764-773. 10.1080/15476286.2024.2379121. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Chen, Pu; Van Oers, Tayla J.; Arutyunova, Elena; Fischer, Conrad; Wang, Chaoxiang et al. (2024). A Structural Comparison of Oral SARS-CoV-2 Drug Candidate Ibuzatrelvir Complexed with the Main Protease (Mpro) of SARS-CoV-2 and MERS-CoV. JACS Au 4(8) , 3217-3227. 10.1021/jacsau.4c00508. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Fraser, Bryan J.; Young, Nicholas J.; Bender, Brian J.; Gahbauer, Stefan; Ilyassov, Olzhas et al. (2025). Large Library Docking and Biophysical Analysis of Small-Molecule TMPRSS2 Inhibitors. Journal of Medicinal Chemistry 68(19) , 19893-19907. 10.1021/acs.jmedchem.4c03089. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Higgins, Melanie A.; Shi, Xinjie; Soler, Jordi; Harland, Jill B.; Parkkila, Taylor et al. (2025). Structure and mechanism of haem-dependent nitrogen–nitrogen bond formation in piperazate synthase. Nature Catalysis 8(3) , 207-217. 10.1038/s41929-024-01280-8. |
CMCF-ID |
Peer-Reviewed Article |
Materials |
| Fraser, Bryan J.; Wilson, Ryan P.; Ferková, Sára; Ilyassov, Olzhas; Lac, Jackie et al. (2025). Structural basis of TMPRSS11D specificity and autocleavage activation. Nature Communications 16(1) . 10.1038/s41467-025-59677-3. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Puumala, Emily; Nandakumar, Meganathan; Yiu, Bonnie; Stogios, Peter J.; Strickland, Benjamin G. et al. (2025). Structure-guided optimization of small molecules targeting Yck2 as a strategy to combat Candida albicans. Nature Communications 16(1) . 10.1038/s41467-025-57346-z. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Nguyen, Quynh Huong; Lai, Chun Heng Royce; Norris, Michael J.; Ng, Dixon; Shah, Megha et al. (2025). A surface lipoprotein on Pasteurella multocida binds complement factor I to promote immune evasion. PLoS Pathogens 21(5) , e1012686. 10.1371/journal.ppat.1012686. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Guo, Shuaiqi; Zahiri, Hossein; Stevens, Corey; Spaanderman, Daniel C.; Milroy, Lech-Gustav et al. (2021). Molecular basis for inhibition of adhesin-mediated bacterial-host interactions through a peptide-binding domain. Cell Reports 37(7) , 110002. 10.1016/j.celrep.2021.110002. [PDB: 6x5v, 6x5w] |
CMCF-ID |
Peer-Reviewed Article |
Agriculture |
| Kwon, Min Chul; Thuring, Jan Willem; Querolle, Olivier; Dai, Xuedong; Verhulst, Tinne et al. (2024). Preclinical efficacy of the potent, selective menin-KMT2A inhibitor JNJ-75276617 (bleximenib) in KMT2A- and NPM1-altered leukemias. Blood 144(11) , 1206-1220. 10.1182/blood.2023022480. [PDB: 9z4x] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Kimani, Serah W.; Noureldin, Mahmoud; Wilson, Brian; Hoffer, Laurent; Green, Stuart R. et al. (2025). OICR-41103 as a chemical probe for the DCAF1 WD40 domain. Communications Biology 8(1) . 10.1038/s42003-025-08491-0. [PDB: 9yv4] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Wang, Mingyu; Du, Grace; Yongo‐Luwawa, Charity; Lu, Angelina; Kinrade, Brett et al. (2025). Peptide‐based ligand antagonists block a
Vibrio cholerae
adhesin. FEBS Letters . 10.1002/1873-3468.70231. [PDB: 9y9w, 9ybq] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Luo, Chuanyun; Paetzel, Mark (2025). Crystal structure of Escherichia coli type I signal peptidase P84A in complex with lipopeptide antibiotic arylomycin A2. Journal of Structural Biology 217(4) , 108260. 10.1016/j.jsb.2025.108260. [PDB: 9nlo] |
CMCF-ID |
Peer-Reviewed Article |
Health |