Publication Beamlines Strategic Pillar
Schellenberg, Matthew J; Wu, Tao; Ritchie, Dustin B; Fica, Sebastian; Staley, Jonathan P et al. (2013). A conformational switch in PRP8 mediates metal ion coordination that promotes pre-mRNA exon ligation. Nature Structural and Molecular Biology 20(6) , 728-734. 10.1038/nsmb.2556. [PDB: 4jk7, 4jk8, 4jk9, 4jka, 4jkb, 4jkc, 4jkh] CMCF-ID Health
Schmidt, Michael M.; Townson, Sharon A.; Andreucci, Amy J.; King, Bracken M.; Schirmer, Emily B. et al. (2013). Crystal Structure of an HSA/FcRn Complex Reveals Recycling by Competitive Mimicry of HSA Ligands at a pH-Dependent Hydrophobic Interface. Structure 21(11) , 1966-1978. 10.1016/j.str.2013.08.022. [PDB: 4k71] CMCF-ID Health
Shala, Agnesa; Patel, Kevin H.; Golemi-Kotra, Dasantila; Audette, Gerald F. (2013). Expression, purification, crystallization and preliminary X-ray analysis of the receiver domain ofStaphylococcus aureusLytR protein. Acta Crystallographica Section F Structural Biology and Crystallization Communications 69(12) , 1418-1421. 10.1107/s1744309113030972. CMCF-ID Health
Strushkevich, Natallia; Gilep, Andrei A.; Shen, Limin; Arrowsmith, Cheryl H.; Edwards, Aled M. et al. (2013). Structural Insights into Aldosterone Synthase Substrate Specificity and Targeted Inhibition. Molecular Endocrinology 27(2) , 315-324. 10.1210/me.2012-1287. [PDB: 4dvq] CMCF-ID Health
Stubbs, Keith A.; Bacik, John‐Paul; Perley‐Robertson, G. Evan; Whitworth, Garrett E.; Gloster, Tracey M. et al. (2013). The Development of Selective Inhibitors of NagZ: Increased Susceptibility of Gram‐Negative Bacteria to β‐Lactams. ChemBioChem 14(15) , 1973-1981. 10.1002/cbic.201300395. [PDB: 4hzm] CMCF-ID Health
Suits, Michael D.; Boraston, Alisdair B. (2013). Structure of the Streptococcus pneumoniae Surface Protein and Adhesin PfbA. PLoS ONE 8(7) , e67190. 10.1371/journal.pone.0067190. [PDB: 3zpp] CMCF-ID Health
Sweeting, Braden; Brown, Eric; Khan, M. Qasim; Chakrabartty, Avijit; Pai, Emil F. et al. (2013). N-Terminal Helix-Cap in α-Helix 2 Modulates β-State Misfolding in Rabbit and Hamster Prion Proteins. PLoS ONE 8(5) , e63047. 10.1371/journal.pone.0063047. [PDB: 4hls, 4hmm, 4hmr] CMCF-ID Health
Tchigvintsev, Anatoli; Tchigvintsev, Dmitri; Flick, Robert; Popovic, Ana; Dong, Aiping et al. (2013). Biochemical and Structural Studies of Conserved Maf Proteins Revealed Nucleotide Pyrophosphatases with a Preference for Modified Nucleotides. Chemistry & Biology 20(11) , 1386-1398. 10.1016/j.chembiol.2013.09.011. [PDB: 4heb] CMCF-ID Health
Trempe, Jean-François; Sauvé, Véronique; Grenier, Karl; Seirafi, Marjan; Tang, Matthew Y. et al. (2013). Structure of Parkin Reveals Mechanisms for Ubiquitin Ligase Activation. Science 340(6139) , 1451-1455. 10.1126/science.1237908. [PDB: 4k7d] CMCF-ID Health
van Kasteren, Puck B.; Bailey-Elkin, Ben A.; James, Terrence W.; Ninaber, Dennis K.; Beugeling, Corrine et al. (2013). Deubiquitinase function of arterivirus papain-like protease 2 suppresses the innate immune response in infected host cells. Proceedings of the National Academy of Sciences of the United States of America 110(9) , E838-E847. 10.1073/pnas.1218464110. [PDB: 4ium] CMCF-ID Health
van Straaten, Karin E.; Ko, Jong Bum; Jagdhane, Rajendra; Anjum, Shazia; Palmer, David R.J. et al. (2013). The Structure of NtdA, a Sugar Aminotransferase Involved in the Kanosamine Biosynthetic Pathway in Bacillus subtilis, Reveals a New Subclass of Aminotransferases. Journal of Biological Chemistry 288(47) , 34121-34130. 10.1074/jbc.m113.500637. [PDB: 4k2b, 4k2i, 4k2m] CMCF-ID Health
Vinaik, Roohi; Kozlov, Guennadi; Gehring, Kalle (2013). Structure of the Non-Catalytic Domain of the Protein Disulfide Isomerase-Related Protein (PDIR) Reveals Function in Protein Binding. PLoS ONE 8(4) , e62021. 10.1371/journal.pone.0062021. CMCF-ID Health
Wu, Hong; Siarheyeva, Alena; Zeng, Hong; Lam, Robert; Dong, Aiping et al. (2013). Crystal structures of the human histone H4K20 methyltransferases SUV420H1 and SUV420H2. FEBS Letters 587(23) , 3859-3868. 10.1016/j.febslet.2013.10.020. [PDB: 3s8p] CMCF-ID Health
Wu, Hong; Zeng, Hong; Dong, Aiping; Li, Fengling; He, Hao et al. (2013). Structure of the Catalytic Domain of EZH2 Reveals Conformational Plasticity in Cofactor and Substrate Binding Sites and Explains Oncogenic Mutations. PLoS ONE 8(12) , e83737. 10.1371/journal.pone.0083737. [PDB: 4mi0] CMCF-ID Health
Zhang, Xiaolu Linda; Tibbits, Glen F.; Paetzel, Mark (2013). The structure of cardiac troponin C regulatory domain with bound Cd2+reveals a closed conformation and unique ion coordination. Acta Crystallographica Section D Biological Crystallography 69(5) , 722-734. 10.1107/s0907444913001182. [PDB: 3sd6, 4gje, 4gjf, 4gjg] CMCF-BM, CMCF-ID Health