Publication Beamlines Strategic Pillar
Norman, Mark H.; Andrews, Kristin L.; Bo, Yunxin Y.; Booker, Shon K.; Caenepeel, Sean et al. (2012). Selective Class I Phosphoinositide 3-Kinase Inhibitors: Optimization of a Series of Pyridyltriazines Leading to the Identification of a Clinical Candidate, AMG 511. Journal of Medicinal Chemistry 55(17) , 7796-7816. 10.1021/jm300846z. [PDB: 4flh] CMCF-ID Health
O'Sullivan, Valerie J.; Barrette-Ng, Isabelle; Hommema, Eric; Hermanson, Greg T.; Schofield, Mark et al. (2012). Development of a Tetrameric Streptavidin Mutein with Reversible Biotin Binding Capability: Engineering a Mobile Loop as an Exit Door for Biotin. PLoS ONE 7(4) , e35203. 10.1371/journal.pone.0035203. CMCF-ID Health
Pfoh, Roland; Li, Angela; Chakrabarti, Nilmadhab; Payandeh, Jian; Pomès, Régis et al. (2012). Structural asymmetry in the magnesium channel CorA points to sequential allosteric regulation. Proceedings of the National Academy of Sciences of the United States of America 109(46) , 18809-18814. 10.1073/pnas.1209018109. [PDB: 4eeb, 4eed] CMCF-ID Health
Purohit, Meena K.; Poduch, Ewa; Wei, Lianhu William; Crandall, Ian Edward; To, Terrence et al. (2012). Novel Cytidine-Based Orotidine-5′-Monophosphate Decarboxylase Inhibitors with an Unusual Twist. Journal of Medicinal Chemistry 55(22) , 9988-9997. 10.1021/jm301176r. [PDB: 4hib] CMCF-ID Health
Ratto, Marcelo H.; Leduc, Yvonne A.; Valderrama, Ximena P.; van Straaten, Karin E.; Delbaere, Louis T. J. et al. (2012). The nerve of ovulation-inducing factor in semen. Proceedings of the National Academy of Sciences of the United States of America 109(37) , 15042-15047. 10.1073/pnas.1206273109. [PDB: 4efv] CMCF-ID Health
Safaee, Nozhat; Kozlov, Guennadi; Noronha, Anne M.; Xie, Jingwei; Wilds, Christopher J. et al. (2012). Interdomain Allostery Promotes Assembly of the Poly(A) mRNA Complex with PABP and eIF4G. Molecular Cell 48(3) , 375-386. 10.1016/j.molcel.2012.09.001. [PDB: 4f02] CMCF-ID Health
Samborska, Bożena; Kimber, Matthew S. (2012). A Dodecameric CcmK2 Structure Suggests β-Carboxysomal Shell Facets Have a Double-Layered Organization. Structure 20(8) , 1353-1362. 10.1016/j.str.2012.05.013. CMCF-ID Materials
Sarhan, Maen F.; Tung, Ching-Chieh; Van Petegem, Filip; Ahern, Christopher A. (2012). Crystallographic basis for calcium regulation of sodium channels. Proceedings of the National Academy of Sciences of the United States of America 109(9) , 3558-3563. 10.1073/pnas.1114748109. [PDB: 4djc] CMCF-ID Health
Schroeder, Gretchen M.; Wei, Donna; Banfi, Patrizia; Cai, Zhen-Wei; Lippy, Jonathan et al. (2012). Pyrazole and pyrimidine phenylacylsulfonamides as dual Bcl-2/Bcl-xL antagonists. Bioorganic and Medicinal Chemistry Letters 22(12) , 3951-3956. 10.1016/j.bmcl.2012.04.106. [PDB: 4ehr] CMCF-ID Health
Shi, Rong; Munger, Christine; Kalan, Lindsay; Sulea, Traian; Wright, Gerard D. et al. (2012). Sulfonation of glycopeptide antibiotics by sulfotransferase StaL depends on conformational flexibility of aglycone scaffold. Proceedings of the National Academy of Sciences of the United States of America 109(29) , 11824-11829. 10.1073/pnas.1205377109. CMCF-ID Health
Shniffer, Adin; Visschedyk, Danielle D.; Ravulapalli, Ravikiran; Suarez, Giovanni; Turgeon, Zachari J. et al. (2012). Characterization of an Actin-targeting ADP-ribosyltransferase from Aeromonas hydrophila. Journal of Biological Chemistry 287(44) , 37030-37041. 10.1074/jbc.m112.397612. [PDB: 4fml] CMCF-ID Health
Siarheyeva, Alena; Senisterra, Guillermo; Allali-Hassani, Abdellah; Dong, Aiping; Dobrovetsky, Elena et al. (2012). An Allosteric Inhibitor of Protein Arginine Methyltransferase 3. Structure 20(8) , 1425-1435. 10.1016/j.str.2012.06.001. [PDB: 3smq] CMCF-ID Health
Tonkin, Michelle L.; Crawford, Joanna; Lebrun, Maryse L.; Boulanger, Martin J. (2012). Babesia divergensandNeospora caninumapical membrane antigen 1 structures reveal selectivity and plasticity in apicomplexan parasite host cell invasion. Protein Science 22(1) , 114-127. 10.1002/pro.2193. [PDB: 4apl] CMCF-ID Health
Ukpabi, Georgia; Takayama, Shin-ichi J.; Mauk, A.Grant; Murphy, Michael E.P. (2012). Inactivation of the Heme Degrading Enzyme IsdI by an Active Site Substitution That Diminishes Heme Ruffling. Journal of Biological Chemistry 287(41) , 34179-34188. 10.1074/jbc.m112.393249. [PDB: 4fnh] CMCF-ID Health
van Straaten, Karin E.; Routier, Francoise H.; Sanders, David A. R. (2012). Towards the crystal structure elucidation of eukaryotic UDP-galactopyranose mutase. Acta Crystallographica Section F Structural Biology and Crystallization Communications 68(4) , 455-459. 10.1107/s1744309112006914. CMCF-ID Health