Conly, Cuylar J. T.; Skovpen, Yulia V.; Li, Shuo; Palmer, David R. J.; Sanders, David A. R. et al. (2014). Tyrosine 110 Plays a Critical Role in Regulating the Allosteric Inhibition of Campylobacter jejuni Dihydrodipicolinate Synthase by Lysine. Biochemistry 53(47) , 7396-7406. 10.1021/bi5012157. [PDB: 4ly8, 4m19, 4mlj, 4mlr, 4r53] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
Cottrell, Kevin M.; Briggs, Kimberly J.; Tsai, Alice; Tonini, Matthew R.; Whittington, Douglas A. et al. (2025). Discovery of TNG462: A Highly Potent and Selective MTA-Cooperative PRMT5 Inhibitor to Target Cancers with MTAP Deletion. Journal of Medicinal Chemistry 68(5) , 5097-5119. 10.1021/acs.jmedchem.4c03067. [PDB: 9n3o] |
CMCF-BM |
Peer-Reviewed Article |
Health |
Crowe, Adam M.; Workman, Sean D.; Watanabe, Nobuhiko; Worrall, Liam J.; Strynadka, Natalie C. J. et al. (2018). IpdAB, a virulence factor in
Mycobacterium tuberculosis
, is a cholesterol ring-cleaving hydrolase. Proceedings of the National Academy of Sciences of the United States of America 115(15) , E3378-E3387. 10.1073/pnas.1717015115. [PDB: 6co6, 6co9, 6coj, 6con] |
CMCF-BM |
Peer-Reviewed Article |
Health |
Crowe, A.M.; Workman, S.D.; Watanabe, N.; Worrall, L.J.; Strynadka, N.C.J. et al. (2018). Crystal structure of Mycobacterium tuberculosis IpdAB. Protein Data Bank: 6con. |
CMCF-BM |
PDB Deposition |
Health |
Crowe, A.M.; Workman, S.D.; Watanabe, N.; Worrall, L.J.; Strynadka, N.C.J. et al. (2018). Crystal structure of Rhodococcus jostii RHA1 IpdAB E105A COCHEA-COA complex. Protein Data Bank: 6coj. |
CMCF-BM |
PDB Deposition |
Health |
Crowe, A.M.; Workman, S.D.; Watanabe, N.; Worrall, L.J.; Strynadka, N.C.J. et al. (2018). Crystal structure of Rhodococcus jostii RHA1 IpdAB COCHEA-COA complex. Protein Data Bank: 6co9. |
CMCF-BM |
PDB Deposition |
Health |
Crowe, A.M.; Workman, S.D.; Watanabe, N.; Worrall, L.J.; Strynadka, N.C.J. et al. (2018). Crystal structure of Rhodococcus jostii RHA1 IpdAB. Protein Data Bank: 6co6. |
CMCF-BM |
PDB Deposition |
Health |
Culp, E.J.; Sychantha, D.; Hobson, C.; Pawlowski, A.J.; Prehna, G. et al. (2022). Crystal structure of Escherichia coli ClpP covalently inhibited by clipibicyclene. Protein Data Bank: 7mk5. |
CMCF-BM |
PDB Deposition |
Health |
Cuskin, Fiona; Lowe, Elisabeth C.; Temple, Max J.; Zhu, Yanping; Cameron, Elizabeth A. et al. (2015). Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism. Nature 517(7533) , 165-169. 10.1038/nature13995. [PDB: 4c1r, 4c1s] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
Cygler, M.; Chung, I.Y.W. (2021). Structure of Legionella Effector LegA15. Protein Data Bank: 7kj6. |
CMCF-BM |
PDB Deposition |
Health |
Després, Philippe C.; Dubé, Alexandre K.; Picard, Marie-Ève; Grenier, Jordan; Shi, Rong et al. (2024). Compensatory mutations potentiate constructive neutral evolution by gene duplication. Science 385(6710) , 770-775. 10.1126/science.ado5719. [PDB: 8vll, 8vlm] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
Dong, Cheng; Nakagawa, Reiko; Oyama, Kyohei; Yamamoto, Yusuke; Zhang, Weilian et al. (2020). Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19. eLife 9. 10.7554/elife.58675. [PDB: 6wat, 6wau] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
Doyle, Liam; Ovchinnikova, Olga G.; Myler, Katharine; Mallette, Evan; Huang, Bo-Shun et al. (2019). Biosynthesis of a conserved glycolipid anchor for Gram-negative bacterial capsules. Nature Chemical Biology 15(6) . 10.1038/s41589-019-0276-8. [PDB: 6mgb, 6mgc, 6mgd] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
Eigenbrot, C.; Yu, C. (2015). EGFR kinase (T790M/L858R) with inhibitor compound 15: ~{N}-(7-chloranyl-1~{H}-indazol-3-yl)-7,7-dimethyl-2-(1~{H}-pyrazol-4-yl)-5~{H}-furo[3,4-d]pyrimidin-4-amine. Protein Data Bank: 5edq. |
CMCF-BM |
PDB Deposition |
Health |
Eigenbrot, C.; Yu, C. (2015). EGFR kinase (T790M/L858R) apo. Protein Data Bank: 5edp. |
CMCF-BM |
PDB Deposition |
Health |