| Pérez-Vargas, Jimena; Worrall, Liam J.; Olmstead, Andrea D.; Ton, Anh-Tien; Lee, Jaeyong et al. (2023). A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants. Emerging Microbes and Infections 12(2) . 10.1080/22221751.2023.2246594. [PDB: 8cyu, 8cyz, 8sxr] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Persch, Elke (2015). Binding to large enzyme pockets: small-molecule inhibitors of trypanothione reductase.. Supervisor: Diederich, Francois. Switzerland: Eidgenoessiche Hochschule Zuerich. . |
CMCF-BM |
Doctoral Thesis |
Health |
| Persch, Elke; Bryson, Steve; Todoroff, Nickolay K.; Eberle, Christian; Thelemann, Jonas et al. (2014). Binding to Large Enzyme Pockets: Small-Molecule Inhibitors of Trypanothione Reductase. ChemMedChem , 1880-1891. 10.1002/cmdc.201402032. [PDB: 4nev] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Petraccione, Kaylee; Ali, Mohamed G. H.; Cyr, Normand; Wahba, Haytham M.; Stocker, Timothy et al. (2024). An LIR motif in the Rift Valley fever virus NSs protein is critical for the interaction with LC3 family members and inhibition of autophagy. PLoS Pathogens 20(3) , e1012093. 10.1371/journal.ppat.1012093. [PDB: 8t2m] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Pham, N. T. Hang; Létourneau, Myriam; Fortier, Marlène; Bégin, Gabriel; Al-Abdul-Wahid, M. Sameer et al. (2021). Perturbing dimer interactions and allosteric communication modulates the immunosuppressive activity of human galectin-7. Journal of Biological Chemistry 297(5) , 101308. 10.1016/j.jbc.2021.101308. [PDB: 6vtp, 6vtr] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Pham, N.T.H.; Calmettes, C.; Doucet, N. (2023). Crystal structure of R14A-R20A human Galectin-7 mutant in presence of lactose. Protein Data Bank: 7tro. |
CMCF-BM |
PDB Deposition |
Health |
| Pham, N.T.H.; Calmettes, C.; Doucet, N. (2023). Crystal structure of R14A-R20A human Galectin-7 mutant. Protein Data Bank: 7trn. |
CMCF-BM |
PDB Deposition |
Health |
| Pham, N.T.H.; Calmettes, C.; Doucet, N. (2023). Crystal structure of D94A human Galectin-7 mutant. Protein Data Bank: 7tky. |
CMCF-BM |
PDB Deposition |
Health |
| Pham, N.T.H.; Calmettes, C.; Doucet, N. (2023). Crystal structure of R14A human Galectin-7 mutant in presence of 4-O-beta-D-Galactopyranosyl-D-glucose. Protein Data Bank: 7tkx. |
CMCF-BM |
PDB Deposition |
Health |
| Pham, N.T.H.; Calmettes, C.; Doucet, N. (2023). Crystal structure of D103A human Galectin-7 mutant in presence of lactose. Protein Data Bank: 7rdg. |
CMCF-BM |
PDB Deposition |
Health |
| Pham, N.T.H.; Calmettes, C.; Doucet, N. (2023). Crystal structure of D103A human Galectin-7 mutant. Protein Data Bank: 7n96. |
CMCF-BM |
PDB Deposition |
Health |
| Pham, N.T.H.; Calmettes, C.; Doucet, N. (2023). Crystal structure of R20A-R22A human Galectin-7 mutant. Protein Data Bank: 7n8g. |
CMCF-BM |
PDB Deposition |
Health |
| Pham, N.T.H.; Calmettes, C.; Doucet, N. (2023). Crystal structure of R22A human Galectin-7 mutant in presence of Lactose. Protein Data Bank: 7n8d. |
CMCF-BM |
PDB Deposition |
Health |
| Pham, N.T.H.; Calmettes, C.; Doucet, N. (2023). Crystal structure of R22A human Galectin-7 mutant. Protein Data Bank: 7n6c. |
CMCF-BM |
PDB Deposition |
Health |
| Pham, N.T.H.; Calmettes, C.; Doucet, N. (2023). Crystal structure of R20A human Galectin-7 mutant. Protein Data Bank: 7n4o. |
CMCF-BM |
PDB Deposition |
Health |