Publication Beamlines Strategic Pillar
Caveney, Nathanael Adam (2021). Structural insights into the modulation of bacterial peptidoglycan synthase activity. Supervisor: Strynadka, Natalie. British Columbia, Canada: University of British Columbia. http://hdl.handle.net/2429/75160. CMCF-BM Health
Gerak, Chloe Ann Nolan (2020). Insights into the inhibition of ETV6 PNT domain polymerization. Supervisor: McIntosh, Lawrence; Roberge, Michel. British Columbia, Canada: University of British Columbia. http://hdl.handle.net/2429/75516. CMCF-BM Health
Hedges, Jason (2024). Biochemical and structural studies of enzymes from the azomycin and beta-ethynylserine biosynthetic pathways. Supervisor: Ryan, Katherine S.. British Columbia, Canada: University of British Columbia. http://hdl.handle.net/2429/79048. CMCF-BM, CMCF-ID Health
Ho, Sui Man (2022). Investigation of diazeniumdiolate formation by the fragin biosynthesis pathway in Burkholderia cenocepacia h111. Supervisor: Ryan, Katherine S.. British Columbia, Canada: University of British Columbia. http://hdl.handle.net/2429/80213. CMCF-BM Health
Rolfe, Nicolas; Myskiw, Dustin; Patton, Matthew T.; Forrester, Taylor J. B.; Kimber, Matthew S. et al. (2025). Sad from Proteobacteria is a Structurally Distinct ALDH3 Enzyme Specialized for the Oxidation of Steroidal Aldehydes. Biochemistry 64(17) , 3735-3744. 10.1021/acs.biochem.5c00213. [PDB: 9nxl] CMCF-BM Health
Rolfe, Nicolas; Schroeter, Kurt L.; Forrester, Taylor JB.; Kimber, Matthew S.; Seah, Stephen YK. et al. (2025). Sal is a proteobacterial bile acid aldolase that repurposes key thiolase catalytic residues for retroaldol cleavage of C5 steroid side chains. Journal of Biological Chemistry 301(8) , 110439. 10.1016/j.jbc.2025.110439. [PDB: 9myr] CMCF-BM Health
Grondin, Julie M.; Duan, Da; Kirlin, Alyssa C.; Abe, Kento T.; Chitayat, Seth et al. (2017). Diverse modes of galacto-specific carbohydrate recognition by a family 31 glycoside hydrolase from Clostridium perfringens. PLoS ONE 12(2) , e0171606. 10.1371/journal.pone.0171606. CLS-APS, CMCF-BM Health
Hamdorf, Matthias; Imhof, Thomas; Bailey-Elkin, Ben; Betz, Janina; Theobald, Sebastian J et al. (2023). The unique ORF8 protein from SARS-CoV-2 binds to human dendritic cells and induces a hyper-inflammatory cytokine storm. Journal of Molecular Cell Biology 15(10) . 10.1093/jmcb/mjad062. CMCF-BM Health
Nam, Sung-Eun (2012). Crystallographic analysis of Bacillus subtilis signal peptide peptidase (SppA). Supervisor: Paetzel, Mark; Harden, Nicolas; Young, Edgar. British Columbia, Canada: Simon Fraser University. https://summit.sfu.ca/item/13913. CMCF-BM Health
Sharafianardakani, Zohreh (2015). Crystallization of Mycobacterium tuberculosis type I signal peptidase. Supervisor: Paetzel, Mark; Craig, Lisa; Pio Frederic. British Columbia, Canada: Simon Fraser University. https://summit.sfu.ca/item/16463. CMCF-BM Health
Barghash, Marim M.; Mabanglo, Mark F.; Hoff, Samuel E.; Brozdnychenko, Dmytro; Wong, Keith S. et al. (2025). Small molecule dysregulation of ClpP activity via bidirectional allosteric pathways. Structure . 10.1016/j.str.2025.07.013. [PDB: 9mjp] CMCF-BM Health
Tran, Norman; Frenette, Aaron; Holyoak, Todd (2025). Structure of the Thomasclavelia ramosa immunoglobulin A protease reveals a modular and minimizable architecture distinct from other immunoglobulin A proteases. Proceedings of the National Academy of Sciences of the United States of America 122(35) . 10.1073/pnas.2503549122. [PDB: 9ekk, 9ekm, 9ekn] CMCF-BM Health
Deschenes, Natalie M; Pérez-Vargas, Jimena; Zhong, Zoe; Thomas, Merrilee; Kenward, Calem et al. (2025). Functional and Structural Characterization of Treatment-Emergent Nirmatrelvir Resistance Mutations at Low Frequencies in the Main Protease (Mpro) Reveals a Unique Evolutionary Route for SARS-CoV-2 to Gain Resistance. Journal of Infectious Diseases . 10.1093/infdis/jiaf294. [PDB: 9pfh, 9pfi] CMCF-BM Health
Krishnan, Shreya S; Shen, Yao; O’Hagan, Treasa B; Matthews, Lindsay A; Weerasinghe, Nuwani W et al. (2025). Asymmetric loading of TnsE regulates Tn7 targeting of DNA replication structures. Nucleic Acids Research 53(11) . 10.1093/nar/gkaf472. [PDB: 9d5l] CMCF-BM Health
Trushar R. PATEL; Carla Stephanie COFFIN; Vanessa MEIER-STEPHENSON; Maulik D. BADMALIA (2023). Polypeptides directed against viral infection and uses thereof. Patent Number: US20230218656A1. CMCF-BM Health