| Li, Mingzong; Konteatis, Zenon; Nagaraja, Nelamangala; Chen, Yue; Zhou, Shubao et al. (2022). Leveraging Structure-Based Drug Design to Identify Next-Generation MAT2A Inhibitors, Including Brain-Penetrant and Peripherally Efficacious Leads. Journal of Medicinal Chemistry 65(6) , 4600-4615. 10.1021/acs.jmedchem.1c01595. [PDB: 7rwg] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Li, Jia; Jia, Yunhua; Lin, Aiyang; Hanna, Michelle; Chelico, Linda et al. (2019). Structure of Ddi2, a highly inducible detoxifying metalloenzyme from Saccharomyces cerevisiae. Journal of Biological Chemistry 294(27) , 10674-10685. 10.1074/jbc.ra118.006394. [PDB: 6dk9, 6dka, 6dkc, 6dkd] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Leung, K.K.; Shilton, B.H. (2013). Oxidized quinone reductase 2 in complex with primaquine. Protein Data Bank: 4fgj. |
CMCF-BM |
PDB Deposition |
Health |
| Leung, K.K.; Shilton, B.H. (2013). Oxidized quinone reductase 2 in complex with chloroquine. Protein Data Bank: 4fgk. |
CMCF-BM |
PDB Deposition |
Health |
| Lee, J.; Kenward, C.; Worrall, L.J.; Vuckovic, M.; Paetzel, M. et al. (2022). Structure of SARS-CoV-2 Mpro in complex with nsp12-nsp13 (C12) cut site sequence. Protein Data Bank: 8ds1. |
CMCF-BM |
PDB Deposition |
Health |
| Lee, J.; Kenward, C.; Worrall, L.J.; Vuckovic, M.; Paetzel, M. et al. (2022). Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp10-nsp11 (C10) cut site sequence (form 2). Protein Data Bank: 8drx. |
CMCF-BM |
PDB Deposition |
Health |
| Lee, J.; Kenward, C.; Worrall, L.J.; Vuckovic, M.; Paetzel, M. et al. (2022). Product structure of SARS-CoV-2 Mpro C145A mutant in complex with nsp7-nsp8 (C7) cut site sequence. Protein Data Bank: 8dru. |
CMCF-BM |
PDB Deposition |
Health |
| Lee, Jaeyong; Taneva, Svetla G.; Holland, Bryan W.; Tieleman, D. Peter; Cornell, Rosemary B. et al. (2014). Structural Basis for Autoinhibition of CTP:Phosphocholine Cytidylyltransferase (CCT), the Regulatory Enzyme in Phosphatidylcholine Synthesis, by Its Membrane-binding Amphipathic Helix. Journal of Biological Chemistry 289(3) , 1742-1755. 10.1074/jbc.m113.526970. [PDB: 4mvc, 4mvd] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Lee, Jaeyong; Kenward, Calem; Worrall, Liam J.; Vuckovic, Marija; Gentile, Francesco et al. (2022). X-ray crystallographic characterization of the SARS-CoV-2 main protease polyprotein cleavage sites essential for viral processing and maturation. Nature Communications 13(1) . 10.1038/s41467-022-32854-4. [PDB: 8dru, 8drx, 8ds1] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Lee, Eunjeong; Tran, Norman; Redzic, Jasmina S.; Singh, Harmanpreet; Alamillo, Lorena et al. (2025). Identifying and controlling inactive and active conformations of a serine protease. Science Advances 11(15) . 10.1126/sciadv.adu7447. [PDB: 9bsh, 9bsm] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Lazarski, A.C.; Worrall, L.J.; Strynadka, N.C.J. (2024). Structure of Alistipes sp. 3-Keto-2-hydroxy-glucal-hydratase AL2. Protein Data Bank: 8v31. |
CMCF-BM |
PDB Deposition |
Health |
| Lazarski, A.C.; Worrall, L.J.; Strynadka, N.C.J. (2024). Structure of P2B11 Glucuronide-3-dehydrogenase. Protein Data Bank: 8tdi. |
CMCF-BM |
PDB Deposition |
Health |
| Lazarski, A.C.; Worrall, L.J.; Strynadka, N.C.J. (2024). Structure of glucose bound Bacteroides thetaiotaomicron 3-Keto-2-hydroxy-glucal-hydratase BT2. Protein Data Bank: 8tde. |
CMCF-BM |
PDB Deposition |
Health |
| Lazarski, A.C.; Worrall, L.J.; Strynadka, N.C.J. (2024). Structure of Bacteroides thetaiotaomicron 3-Keto-2-hydroxy-glucal-hydratase BT2. Protein Data Bank: 8tda. |
CMCF-BM |
PDB Deposition |
Health |
| Lazarski, A.C.; Worrall, L.J.; Strynadka, N.C.J. (2024). Structure of 3K-GlcH bound Bacteroides thetaiotaomicron 3-Keto-beta-glucopyranoside-1,2-Lyase BT1. Protein Data Bank: 8tct. |
CMCF-BM |
PDB Deposition |
Health |