Publication Beamlines Strategic Pillar
Forrester, Taylor J. B.; Lin, Sicheng; Lowary, Todd L.; Kimber, Matthew S. (2025). WrtF from Rhizobium tropici CIAT 899 is a GT-A fold fucosyltransferase that binds its donor nonproductively. Proceedings of the National Academy of Sciences of the United States of America 122(44) . 10.1073/pnas.2512460122. [PDB: 9omh, 9omi] CMCF-BM, CMCF-ID Agriculture
Forrester, T.J.B.; Kimber, M.S. (2025). WrtF fucosyltransferase - GDP-2-deoxy-2-fluoro-beta-L-fucose. Protein Data Bank: 9omn. CMCF-BM Agriculture
Forrester, T.J.B.; Kimber, M.S. (2025). WrtF fucosyltransferase - tetrasaccharide product. Protein Data Bank: 9omm. CMCF-BM Agriculture
Forrester, T.J.B.; Kimber, M.S. (2025). WrtF fucosyltransferase - GDP-beta-L-fucose. Protein Data Bank: 9omj. CMCF-BM Agriculture
Forrester, T.J.B.; Kimber, M.S. (2025). WrtF fucosyltransferase - GDP. Protein Data Bank: 9omi. CMCF-BM Agriculture
Uguen, Mélanie; Shell, Devan J.; Silva, Madhushika; Deng, Yu; Li, Fengling et al. (2025). Potent and selective SETDB1 covalent negative allosteric modulator reduces methyltransferase activity in cells. Nature Communications 16(1) . 10.1038/s41467-025-57005-3. [PDB: 9cuw, 9cux] CMCF-BM Agriculture
kimani, S.; Dong, A.; Li, Y.; Seitova, A.; Mamai, A. et al. (2025). Crystal structure of the human DCAF1 WDR domain in complex with OICR-40120. Protein Data Bank: 9y76. CMCF-BM Agriculture
Rolfe, N.; Myskiw, D.; Patton, M.T.; Forrester, T.J.B.; Kimber, M.S. et al. (2025). Crystal structure of steroid aldehyde dehydrogenase (Sad) from Caldimonas tepidiphilia. Protein Data Bank: 9nxl. CMCF-BM Agriculture
Rolfe, Nicolas; Myskiw, Dustin; Patton, Matthew T.; Forrester, Taylor J. B.; Kimber, Matthew S. et al. (2025). Sad from Proteobacteria is a Structurally Distinct ALDH3 Enzyme Specialized for the Oxidation of Steroidal Aldehydes. Biochemistry 64(17) , 3735-3744. 10.1021/acs.biochem.5c00213. [PDB: 9nxl] CMCF-BM Agriculture
Rolfe, N.; Schroeter, K.L.; Forrester, T.J.B.; Kimber, M.S.; Seah, S.Y.K. et al. (2025). Sal-Shy(DUF35) aldolase from Comamonas testosteroni. Protein Data Bank: 9myr. CMCF-BM Agriculture
Rolfe, Nicolas; Schroeter, Kurt L.; Forrester, Taylor JB.; Kimber, Matthew S.; Seah, Stephen YK. et al. (2025). Sal is a proteobacterial bile acid aldolase that repurposes key thiolase catalytic residues for retroaldol cleavage of C5 steroid side chains. Journal of Biological Chemistry 301(8) , 110439. 10.1016/j.jbc.2025.110439. [PDB: 9myr] CMCF-BM Agriculture
Hamdorf, Matthias; Imhof, Thomas; Bailey-Elkin, Ben; Betz, Janina; Theobald, Sebastian J et al. (2023). The unique ORF8 protein from SARS-CoV-2 binds to human dendritic cells and induces a hyper-inflammatory cytokine storm. Journal of Molecular Cell Biology 15(10) . 10.1093/jmcb/mjad062. CMCF-BM Agriculture
Shaik, M.M.; Brennan, D. (2025). Crystal structure of human 15-PGDH in complex with small molecule compound 1. Protein Data Bank: 9pfl. CMCF-BM Agriculture
Mabanglo, M.F.; Houry, W.A. (2025). Crystal structure of Neisseria meningitidis ClpP protease complex with boronate compound BC8a. Protein Data Bank: 9mjp. CMCF-BM Agriculture
Barghash, Marim M.; Mabanglo, Mark F.; Hoff, Samuel E.; Brozdnychenko, Dmytro; Wong, Keith S. et al. (2025). Small molecule dysregulation of ClpP activity via bidirectional allosteric pathways. Structure . 10.1016/j.str.2025.07.013. [PDB: 9mjp] CMCF-BM Agriculture