Publication Beamlines Strategic Pillar
Mothersole, Robert G.; Kolesnikov, Maxim; Chan, Anson C. K.; Oduro, Emmanuella; Murphy, Michael E. P. et al. (2022). Sequence Divergence in the Arginase Domain of Ornithine Decarboxylase/Arginase in Fusobacteriacea Leads to Loss of Function in Oral Associated Species. Biochemistry 61(13) , 1378-1391. 10.1021/acs.biochem.2c00197. [PDB: 8d27] CMCF-BM Health
Fedoretz-Maxwell, Brooklyn P.; Shin, Catherine H.; MacNeil, Gregory A.; Worrall, Liam J.; Park, Rachel et al. (2022). The Impact of Second Coordination Sphere Methionine-Aromatic Interactions in Copper Proteins. Inorganic Chemistry 61(14) , 5563-5571. 10.1021/acs.inorgchem.2c00030. [PDB: 7tc5] CMCF-BM, CMCF-ID Health
Fakih, Rayan; Sauvé, Véronique; Gehring, Kalle (2022). Structure of the second phosphoubiquitin–binding site in parkin. Journal of Biological Chemistry 298(7) , 102114. 10.1016/j.jbc.2022.102114. [PDB: 7us1] CMCF-BM Health
Lu, Jimmy; Chen, Sizhu Amelia; Khan, Muhammad Bashir; Brassard, Raelynn; Arutyunova, Elena et al. (2022). Crystallization of Feline Coronavirus Mpro With GC376 Reveals Mechanism of Inhibition. Frontiers in Chemistry 10. 10.3389/fchem.2022.852210. [PDB: 7smv, 7sna] CMCF-BM Health
Navas, Laura E.; Zahn, Michael; Bajwa, Harbir; Grigg, Jason C.; Wolf, Megan E. et al. (2022). Characterization of a phylogenetically distinct extradiol dioxygenase involved in the bacterial catabolism of lignin-derived aromatic compounds. Journal of Biological Chemistry 298(5) , 101871. 10.1016/j.jbc.2022.101871. [PDB: 7q2a] CMCF-BM Health
Li, Mingzong; Konteatis, Zenon; Nagaraja, Nelamangala; Chen, Yue; Zhou, Shubao et al. (2022). Leveraging Structure-Based Drug Design to Identify Next-Generation MAT2A Inhibitors, Including Brain-Penetrant and Peripherally Efficacious Leads. Journal of Medicinal Chemistry 65(6) , 4600-4615. 10.1021/acs.jmedchem.1c01595. [PDB: 7rwg] CMCF-BM Health
Sharon, Itai; Grogg, Marcel; Hilvert, Donald; Schmeing, T. Martin (2022). Structure and Function of the β-Asp-Arg Polymerase Cyanophycin Synthetase 2. ACS Chemical Biology 17(3) . 10.1021/acschembio.1c01007. [PDB: 7ta5] CMCF-BM Health
Shen, Yao; Gomez-Blanco, Josue; Petassi, Michael T.; Peters, Joseph E.; Ortega, Joaquin et al. (2022). Structural basis for DNA targeting by the Tn7 transposon. Nature Structural and Molecular Biology 29(2) , 143-151. 10.1038/s41594-022-00724-8. [PDB: 7mbw] CMCF-BM Health
Stille, Julia K.; Tjutrins, Jevgenijs; Wang, Guanyu; Venegas, Felipe A.; Hennecker, Christopher et al. (2022). Design, synthesis and in vitro evaluation of novel SARS-CoV-2 3CLpro covalent inhibitors. European Journal of Medicinal Chemistry 229, 114046. 10.1016/j.ejmech.2021.114046. [PDB: 7mlf] CMCF-BM Health
Bateman, Thomas J.; Shah, Megha; Ho, Timothy Pham; Shin, Hyejin Esther; Pan, Chuxi et al. (2021). A Slam-dependent hemophore contributes to heme acquisition in the bacterial pathogen Acinetobacter baumannii. Nature Communications 12(1) . 10.1038/s41467-021-26545-9. [PDB: 7re4, 7rea, 7red] CMCF-BM, CMCF-ID Health
Pham, N. T. Hang; Létourneau, Myriam; Fortier, Marlène; Bégin, Gabriel; Al-Abdul-Wahid, M. Sameer et al. (2021). Perturbing dimer interactions and allosteric communication modulates the immunosuppressive activity of human galectin-7. Journal of Biological Chemistry 297(5) , 101308. 10.1016/j.jbc.2021.101308. [PDB: 6vtp, 6vtr] CMCF-BM Health
Chung, Ivy Yeuk Wah; Li, Lei; Cygler, Miroslaw (2021). Legionella effector LegA15/AnkH contains an unrecognized cysteine protease-like domain and displays structural similarity to LegA3/AnkD, but differs in host cell localization. Acta Crystallographica Section D: Structural Biology 77(12) . 10.1107/s2059798321010469. [PDB: 7kj6] CMCF-BM Health
Radka, Christopher D.; Aller, Stephen G. (2021). Site 2 of the Yersinia pestis substrate-binding protein YfeA is a dynamic surface metal-binding site. Acta Crystallographica Section F:Structural Biology Communications 77(9) , 286-293. 10.1107/s2053230x21008086. [PDB: 7me1] CMCF-BM Health
Stevenson, James; Ngo, Maria; Brandt, Alicia; Weadge, Joel T.; Suits, Michael D. L. et al. (2021). Analysis of Two SusE-Like Enzymes From Bacteroides thetaiotaomicron Reveals a Potential Degradative Capacity for This Protein Family. Frontiers in Microbiology 12. 10.3389/fmicb.2021.645765. [PDB: 7m1a, 7m1b] CMCF-BM Health
Satishkumar, Nidhi; Alexander, J Andrew N; Poon, Raymond; Buggeln, Emma; Argudín, Maria A et al. (2021). PBP4-mediated β-lactam resistance among clinical strains of Staphylococcus aureus. Journal of Antimicrobial Chemotherapy 76(9) . 10.1093/jac/dkab201. [PDB: 7kcv] CMCF-BM Health