| Mabanglo, Mark F.; Wilson, Brian; Noureldin, Mahmoud; Kimani, Serah W.; Mamai, Ahmed et al. (2024). Crystal structures of DCAF1-PROTAC-WDR5 ternary complexes provide insight into DCAF1 substrate specificity. Nature Communications 15(1) . 10.1038/s41467-024-54500-x. [PDB: 9b9h, 9b9t, 9b9w, 9ba2] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Harris, S.F.; Wu, P. (2024). Mtb GuaB dCBS in complex with inhibitor compound 5. Protein Data Bank: 9dc9. |
CMCF-BM |
PDB Deposition |
Health |
| Harris, S.F.; Wu, P. (2024). Mtb GuaB dCBS in complex with inhibitor G1. Protein Data Bank: 9dc8. |
CMCF-BM |
PDB Deposition |
Health |
| Zhou, Yuebiao; Aliagas, Ignacio; Wang, Shumei; Li, Chun Sing; Liu, Zhiguo et al. (2024). Discovery of potent dihydro-oxazinoquinolinone inhibitors of GuaB for the treatment of tuberculosis. Bioorganic and Medicinal Chemistry Letters , 130026. 10.1016/j.bmcl.2024.130026. [PDB: 9dc8, 9dc9] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Mabanglo, M.F.; Wilson, B.J.; Srivastava, S.; Al-awar, R.; Vedadi, M. et al. (2024). Crystal structure of the binary complex of DCAF1 and WDR5. Protein Data Bank: 9ba2. |
CMCF-BM |
PDB Deposition |
Health |
| Mabanglo, M.F.; Wilson, B.J.; Mamai, A.; Hoffer, L.; Al-awar, R. et al. (2024). Crystal structure of the ternary complex of DCAF1 and WDR5 with PROTAC, OICR-40792. Protein Data Bank: 9b9w. |
CMCF-BM |
PDB Deposition |
Health |
| Mabanglo, M.F.; Wilson, B.J.; Krausser, C.; Hoffer, L.; Al-awar, R. et al. (2024). Crystal structure of the ternary complex of DCAF1 and WDR5 with PROTAC, OICR-40407. Protein Data Bank: 9b9t. |
CMCF-BM |
PDB Deposition |
Health |
| Mabanglo, M.F.; Wilson, B.J.; Alvarez, H.G.; Hoffer, L.; Al-awar, R. et al. (2024). Crystal structure of the ternary complex of DCAF1 and WDR5 with PROTAC, OICR-40333. Protein Data Bank: 9b9h. |
CMCF-BM |
PDB Deposition |
Health |
| Saran, Anshu; Kim, Hey-Min; Manning, Ireland; Hancock, Mark A; Schmitz, Claus et al. (2024). Unveiling the molecular mechanisms of the type IX secretion system's response regulator: Structural and functional insights. PNAS Nexus 3(8) . 10.1093/pnasnexus/pgae316. [PDB: 8ted] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Silva, M.; Dong, A.; Arrowsmith, C.H.; Edwards, A.M.; Halabelian, L. et al. (2024). Crystal Structure of SETDB1 Tudor domain in complex with UNC100016. Protein Data Bank: 9cux. |
CMCF-BM |
PDB Deposition |
Health |
| Silva, M.; Dong, A.; Arrowsmith, C.H.; Edwards, A.M.; Halabelian, L. et al. (2024). Crystal Structure of SETDB1 Tudor domain in complex with UNC100013. Protein Data Bank: 9cuw. |
CMCF-BM |
PDB Deposition |
Health |
| Mabanglo, M.F.; Houry, W.A. (2024). Crystal structure of Neisseria meningitidis ClpP protease in complex with phosphine oxide compound ACP6-12. Protein Data Bank: 8szn. |
CMCF-BM |
PDB Deposition |
Health |
| Mabanglo, M.F.; Houry, W.A. (2024). Crystal structure of E. coli ClpP protease in complex with phosphine oxide compound ACP6-12. Protein Data Bank: 8szm. |
CMCF-BM |
PDB Deposition |
Health |
| Lin, Funing; Mabanglo, Mark F.; Zhou, Jin Lin; Binepal, Gursonika; Barghash, Marim M. et al. (2024). Structure-Based Design and Development of Phosphine Oxides as a Novel Chemotype for Antibiotics that Dysregulate Bacterial ClpP Proteases. Journal of Medicinal Chemistry 67(17) , 15131-15147. 10.1021/acs.jmedchem.4c00773. [PDB: 8szm, 8szn] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Picard, M.-E.; Grenier, G.; Despres, P.C.; Dube, A.K.; Landry, C.R. et al. (2024). Crystal structure of the yeast cytosine deaminase (yCD) E64V-M100W heterodimer. Protein Data Bank: 8vlm. |
CMCF-BM |
PDB Deposition |
Health |