| Rolfe, Nicolas; Schroeter, Kurt L.; Forrester, Taylor JB.; Kimber, Matthew S.; Seah, Stephen YK. et al. (2025). Sal is a proteobacterial bile acid aldolase that repurposes key thiolase catalytic residues for retroaldol cleavage of C5 steroid side chains. Journal of Biological Chemistry 301(8) , 110439. 10.1016/j.jbc.2025.110439. [PDB: 9myr] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Throner, Scott; Feng, Tianshu; Andersen, Jannik N.; Bandi, Madhavi; Engel, Justin L. et al. (2025). Discovery of TNG-6132, a potent, selective, and orally bioavailable USP1 inhibitor. Bioorganic and Medicinal Chemistry Letters 124, 130262. 10.1016/j.bmcl.2025.130262. [PDB: 9n9y] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Tran, Norman; Frenette, Aaron; Holyoak, Todd (2025). Structure of the
Thomasclavelia ramosa
immunoglobulin A protease reveals a modular and minimizable architecture distinct from other immunoglobulin A proteases. Proceedings of the National Academy of Sciences of the United States of America 122(35) . 10.1073/pnas.2503549122. [PDB: 9ekk, 9ekm, 9ekn] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Tran, Norman; Redzic, Jasmina S.; Eisenmesser, Elan Z.; Holyoak, Todd (2025). The structure of the Gemella haemolysans M26 IgA1 protease trypsin-like domain. Acta Crystallographica Section F:Structural Biology Communications 81(4) . 10.1107/s2053230x25001219. [PDB: 9ect] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Uguen, Mélanie; Shell, Devan J.; Silva, Madhushika; Deng, Yu; Li, Fengling et al. (2025). Potent and selective SETDB1 covalent negative allosteric modulator reduces methyltransferase activity in cells. Nature Communications 16(1) . 10.1038/s41467-025-57005-3. [PDB: 9cuw, 9cux] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Zhao, Feipeng; Zhang, Shumin; Wang, Shuo; Reid, Joel W.; Xia, Wei et al. (2025). Anion sublattice design enables superionic conductivity in crystalline oxyhalides. Science 390(6769) , 199-204. 10.1126/science.adt9678. |
CMCF-BM, SXRMB |
Peer-Reviewed Article |
Materials |
| Di Lello, P.; Wells, M.M. (2026). Targeting PTPN22 at non-orthosteric binding sites - a fragment approach. Protein Data Bank: 9yg3. |
CMCF-BM |
PDB Deposition |
Agriculture |
| Di Lello, P.; Wells, M.M. (2026). Targeting PTPN22 at non-orthosteric binding sites - a fragment approach. Protein Data Bank: 9yg1. |
CMCF-BM |
PDB Deposition |
Agriculture |
| Di Lello, P.; Wells, M.M. (2026). Targeting PTPN22 at non-orthosteric binding sites - a fragment approach. Protein Data Bank: 9yg0. |
CMCF-BM |
PDB Deposition |
Agriculture |
| Mellouk, A.; Calmettes, C. (2026). Crystal structure of Class-3 OPX WzaB from Myxococcus xanthus. Protein Data Bank: 9n9a. |
CMCF-BM |
PDB Deposition |
Agriculture |
| Sachark, K.; Van Schepdael, M.; Winters, K.L.; Prehna, G. (2026). Crystal structure of VgrS from Salmonella Typhimurium. Protein Data Bank: 9mlp. |
CMCF-BM |
PDB Deposition |
Agriculture |
| Van Schepdael, M.A.; Prehna, G. (2026). Structure of SciW variant L66A bound to the Rhs1 transmembrane domain. Protein Data Bank: 9mvg. |
CMCF-BM |
PDB Deposition |
Agriculture |
| Chen, P.; Lamer, T.; Vederas, J.C.; Lemieux, M.J. (2025). Crystal structures of a cyanobacterial DAP epimerase bound to D,L-alpha-methyl DAP. Protein Data Bank: 9mrv. |
CMCF-BM |
PDB Deposition |
Agriculture |
| Chen, P.; Lamer, T.; Vederas, J.C.; Lemieux, M.J. (2025). Crystal structures of a cyanobacterial DAP epimerase bound to either D,L-aziDAP or D,L-alpha-methyl DAP. Protein Data Bank: 9mro. |
CMCF-BM |
PDB Deposition |
Agriculture |
| Ereno-Orbea, J.; Sicard, T.; Julien, J.-P. (2025). Crystal structure of human CD22 Ig domains 1-3 in complex with modified sialoside 1B. Protein Data Bank: 9rob. |
CMCF-BM |
PDB Deposition |
Agriculture |