Chen, P.; Lamer, T.; Vederas, J.C.; Lemieux, M.J. (2025). Crystal structures of a cyanobacterial DAP epimerase bound to D,L-alpha-methyl DAP. Protein Data Bank: 9mrv. |
CMCF-BM |
PDB Deposition |
Agriculture |
Chen, P.; Lamer, T.; Vederas, J.C.; Lemieux, M.J. (2025). Crystal structures of a cyanobacterial DAP epimerase bound to either D,L-aziDAP or D,L-alpha-methyl DAP. Protein Data Bank: 9mro. |
CMCF-BM |
PDB Deposition |
Agriculture |
Colussi, Danielle M.; Grainger, Ryan; Noble, Megan; Lake, Taylor; Junop, Murray et al. (2025). Disrupting the network of co-evolving amino terminal domain residues relieves mitochondrial calcium uptake inhibition by MCUb. Computational and Structural Biotechnology Journal 27, 190-213. 10.1016/j.csbj.2024.12.007. [PDB: 8urg] |
CMCF-BM |
Peer-Reviewed Article |
Health |
Cottrell, Kevin M.; Briggs, Kimberly J.; Tsai, Alice; Tonini, Matthew R.; Whittington, Douglas A. et al. (2025). Discovery of TNG462: A Highly Potent and Selective MTA-Cooperative PRMT5 Inhibitor to Target Cancers with MTAP Deletion. Journal of Medicinal Chemistry 68(5) , 5097-5119. 10.1021/acs.jmedchem.4c03067. [PDB: 9n3o] |
CMCF-BM |
Peer-Reviewed Article |
Health |
Deschenes, Natalie M; Pérez-Vargas, Jimena; Zhong, Zoe; Thomas, Merrilee; Kenward, Calem et al. (2025). Functional and Structural Characterization of Treatment-Emergent Nirmatrelvir Resistance Mutations at Low Frequencies in the Main Protease (Mpro) Reveals a Unique Evolutionary Route for SARS-CoV-2 to Gain Resistance. Journal of Infectious Diseases . 10.1093/infdis/jiaf294. [PDB: 9pfh, 9pfi] |
CMCF-BM |
Peer-Reviewed Article |
Health |
Frigon, L.; Pascal, J.M. (2025). PARP4 BRCT domain F39A mutant. Protein Data Bank: 9dfr. |
CMCF-BM |
PDB Deposition |
Health |
Frigon, L.; Pascal, J.M. (2025). PARP4 BRCT domain F39Q mutant. Protein Data Bank: 9dfq. |
CMCF-BM |
PDB Deposition |
Health |
Frigon, L.; Pascal, J.M. (2025). PARP4 BRCT domain K23/24Q mutant. Protein Data Bank: 9dfp. |
CMCF-BM |
PDB Deposition |
Health |
Frigon, L.; Pascal, J.M. (2025). PARP4 BRCT domain K31Q mutant. Protein Data Bank: 9dfo. |
CMCF-BM |
PDB Deposition |
Health |
Grainger, R.; Colussi, D.C.; Noble, M.; Junop, M.; Stathopulos, P.B. et al. (2025). Human mitochondrial calcium uniporter crystal structure (residues 74-165 resolved) with lithium. Protein Data Bank: 8urg. |
CMCF-BM |
PDB Deposition |
Health |
Holyoak, T.; Tran, N. (2025). Staphylococcus aureus exfoliative toxin A D164E variant. Protein Data Bank: 9bsm. |
CMCF-BM |
PDB Deposition |
Health |
Holyoak, T.; Tran, N. (2025). Staphylococcus aureus exfoliative toxin A D164A variant. Protein Data Bank: 9bsh. |
CMCF-BM |
PDB Deposition |
Health |
Kenward, C.; Mosimann, W.A.; Worrall, L.J.; Strynadka, N.C.J. (2025). Crystal structure of SARS-CoV-2 Mpro Mutant P132H. Protein Data Bank: 9pfi. |
CMCF-BM |
PDB Deposition |
Agriculture |
Kenward, C.; Mosimann, W.A.; Worrall, L.J.; Strynadka, N.C.J. (2025). Crystal structure of SARS-CoV-2 Mpro Mutant P132H with C5a. Protein Data Bank: 9pfh. |
CMCF-BM |
PDB Deposition |
Agriculture |
Kimani, S.; Dong, A.; Hoffmann, L.; Nemec, V.; Ackloo, S. et al. (2025). Crystal structure of the human WDR5 in complex with LH168 compound. Protein Data Bank: 9d5z. |
CMCF-BM |
PDB Deposition |
Health |