Publication Beamlines Strategic Pillar
Barghash, Marim M.; Mabanglo, Mark F.; Hoff, Samuel E.; Brozdnychenko, Dmytro; Wong, Keith S. et al. (2025). Small molecule dysregulation of ClpP activity via bidirectional allosteric pathways. Structure . 10.1016/j.str.2025.07.013. [PDB: 9mjp] CMCF-BM Agriculture
Dodda, Leela S.; Campos, Sebastien; Ciccone, David; Carreiro, Samantha; Leit, Silvana et al. (2025). Knowledge and Structure-Based Drug Design of 15-PGDH Inhibitors. Journal of Medicinal Chemistry 68(17) , 18436-18462. 10.1021/acs.jmedchem.5c01231. [PDB: 9pfl] CMCF-BM Agriculture
Hamdorf, Matthias; Imhof, Thomas; Bailey-Elkin, Ben; Betz, Janina; Theobald, Sebastian J et al. (2023). The unique ORF8 protein from SARS-CoV-2 binds to human dendritic cells and induces a hyper-inflammatory cytokine storm. Journal of Molecular Cell Biology 15(10) . 10.1093/jmcb/mjad062. CMCF-BM Agriculture
Rolfe, Nicolas; Myskiw, Dustin; Patton, Matthew T.; Forrester, Taylor J. B.; Kimber, Matthew S. et al. (2025). Sad from Proteobacteria is a Structurally Distinct ALDH3 Enzyme Specialized for the Oxidation of Steroidal Aldehydes. Biochemistry 64(17) , 3735-3744. 10.1021/acs.biochem.5c00213. [PDB: 9nxl] CMCF-BM Agriculture
Rolfe, Nicolas; Schroeter, Kurt L.; Forrester, Taylor JB.; Kimber, Matthew S.; Seah, Stephen YK. et al. (2025). Sal is a proteobacterial bile acid aldolase that repurposes key thiolase catalytic residues for retroaldol cleavage of C5 steroid side chains. Journal of Biological Chemistry 301(8) , 110439. 10.1016/j.jbc.2025.110439. [PDB: 9myr] CMCF-BM Agriculture
Tran, Norman; Frenette, Aaron; Holyoak, Todd (2025). Structure of the Thomasclavelia ramosa immunoglobulin A protease reveals a modular and minimizable architecture distinct from other immunoglobulin A proteases. Proceedings of the National Academy of Sciences of the United States of America 122(35) . 10.1073/pnas.2503549122. [PDB: 9ekk, 9ekm, 9ekn] CMCF-BM Agriculture
Vergunst, Kathleen L.; Langelaan, David N. (2022). The N-terminal tail of the hydrophobin SC16 is not required for rodlet formation. Scientific Reports 12(1) . 10.1038/s41598-021-04223-6. CMCF-BM Agriculture
Abraham, N.; Schroeter, K.L.; Kimber, M.S.; Seah, S.Y.K. (2022). Structure-Function characterization of an aldo-keto reductase involved in detoxification of the mycotoxin, deoxynivalenol. Protein Data Bank: 7utf. CMCF-BM Agriculture
Ali, M.G.H.; Wahba, H.M.; Cyr, N.; Omichinski, J.G. (2024). Crystal structure of GABARAP in complex with the LIR of NSs4. Protein Data Bank: 8t2m. CMCF-BM Agriculture
Ayanath Kuttiyatveetil, J.R.; Pascal, J.M. (2022). Mouse PARP13/ZAP ZnF5-WWE1-WWE2 bound to ADPr. Protein Data Bank: 7sz3. CMCF-BM Agriculture
Ayanath Kuttiyatveetil, J.R.; Pascal, J.M. (2022). Mouse PARP13/ZAP ZnF5-WWE1-WWE2 bound to ATP. Protein Data Bank: 7sz2. CMCF-BM Agriculture
Chan, A.C.; Kolesnikov, M.; Murphy, M.E. (2022). Arginase Domain of Ornithine Decarboxylase/Arginase from Fusobacterium nucleatum. Protein Data Bank: 8d27. CMCF-BM Agriculture
Chan, A.C.; Wolthers, K.R.; Murphy, M.E. (2023). Heme-bound flavodoxin FldH from Fusobacterium nucleatum. Protein Data Bank: 8g64. CMCF-BM Agriculture
Chen, P.; Lamer, T.; Vederas, J.C.; Lemieux, M.J. (2025). Crystal structures of a cyanobacterial DAP epimerase bound to D,L-alpha-methyl DAP. Protein Data Bank: 9mrv. CMCF-BM Agriculture
Chen, P.; Lamer, T.; Vederas, J.C.; Lemieux, M.J. (2025). Crystal structures of a cyanobacterial DAP epimerase bound to either D,L-aziDAP or D,L-alpha-methyl DAP. Protein Data Bank: 9mro. CMCF-BM Agriculture