Publication Beamlines Strategic Pillar
Schenkel, Laurie B.; Molina, Jennifer R.; Swinger, Kerren K.; Abo, Ryan; Blackwell, Danielle J. et al. (2021). A potent and selective PARP14 inhibitor decreases protumor macrophage gene expression and elicits inflammatory responses in tumor explants. Cell Chemical Biology 28(8) . 10.1016/j.chembiol.2021.02.010. [PDB: 6we2] CMCF-ID Health
Rathinaswamy, Manoj K; Gaieb, Zied; Fleming, Kaelin D; Borsari, Chiara; Harris, Noah J et al. (2021). Disease-related mutations in PI3Kγ disrupt regulatory C-terminal dynamics and reveal a path to selective inhibitors. eLife 10. 10.7554/elife.64691. [PDB: 7jwe, 7jwz, 7jx0] CMCF-ID Health
Chung, Ivy Y. W.; Li, Lei; Tyurin, Oleg; Gagarinova, Alla; Wibawa, Raissa et al. (2021). Structural and functional study of Legionella pneumophila effector RavA. Protein Science 30(5) . 10.1002/pro.4057. [PDB: 6wo6] CMCF-ID Health
Lin, Chang Sheng-Huei; Chan, Anson C.K.; Vermeulen, Jenny; Brockerman, Jacob; Soni, Arvind S. et al. (2021). Peptidoglycan binding by a pocket on the accessory NTF2-domain of Pgp2 directs helical cell shape of Campylobacter jejuni. Journal of Biological Chemistry 296, 100528. 10.1016/j.jbc.2021.100528. [PDB: 6xj7] CMCF-BM Health
Langston, Steven P.; Grossman, Stephen; England, Dylan; Afroze, Roushan; Bence, Neil et al. (2021). Discovery of TAK-981, a First-in-Class Inhibitor of SUMO-Activating Enzyme for the Treatment of Cancer. Journal of Medicinal Chemistry 64(5) . 10.1021/acs.jmedchem.0c01491. [PDB: 6xog, 6xoh] CMCF-ID Health
Huang, Ji; Fraser, Marie E. (2021). Second distinct conformation of the phosphohistidine loop in succinyl-CoA synthetase. Acta Crystallographica Section D: Structural Biology 77(3) , 357-368. 10.1107/s2059798321000334. [PDB: 7jj0, 7jkr] CMCF-ID Health
Dragovich, Peter S.; Pillow, Thomas H.; Blake, Robert A.; Sadowsky, Jack D.; Adaligil, Emel et al. (2021). Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 2: Improvement of In Vitro Antiproliferation Activity and In Vivo Antitumor Efficacy. Journal of Medicinal Chemistry 64(5) . 10.1021/acs.jmedchem.0c01846. [PDB: 7khl] CMCF-ID Health
McDougall, Matthew; McEleney, Kevin; Francisco, Olga; Trieu, Benchmen; Ogbomo, Efehi Kelly et al. (2018). Reductive power of the archaea right-handed coiled coil nanotube (RHCC-NT) and incorporation of mercury clusters inside protein cages. Journal of Structural Biology 203(3) , 281-287. 10.1016/j.jsb.2018.05.013. CMCF-BM Health
Miersch, Shane; Li, Zhijie; Saberianfar, Reza; Ustav, Mart; Case, James Brett et al. (2020). Tetravalent SARS-CoV-2 Neutralizing Antibodies Show Enhanced Potency and Resistance to Escape Mutations. Vibrational Spectroscopy . 10.1101/2020.10.31.362848. [PDB: 7klg, 7klh] CMCF-BM Health
Scholl, Connor L.; Tsuda, Sakae; Graham, Laurie A.; Davies, Peter L. (2021). Crystal waters on the nine polyproline type II helical bundle springtail antifreeze protein from Granisotoma rainieri match the ice lattice. FEBS Journal 288(14) . 10.1111/febs.15717. [PDB: 7jjv] CMCF-ID Health
Vatta, Maritza; Lyons, Bronwyn; Heney, Kayla A.; Lidster, Taylor; Merrill, A. Rod et al. (2021). Mapping the DNA-Binding Motif of Scabin Toxin, a Guanine Modifying Enzyme from Streptomyces scabies. Toxins 13(1) , 55. 10.3390/toxins13010055. [PDB: 6vuv, 6vv4, 6vvf] CMCF-ID Health
Lu, Xiaocen; Wen, Yurong; Zhang, Shuce; Zhang, Wei; Chen, Yilun et al. (2020). Improved Photocleavable Proteins with Faster and More Efficient Dissociation. Journal of Nanoparticle Research . 10.1101/2020.12.10.419556. [PDB: 7dmx, 7dna, 7dnb] CMCF-ID Health
Gerak, Chloe A.N.; Cho, Sophia Y.; Kolesnikov, Maxim; Okon, Mark; Murphy, Michael E.P. et al. (2021). Biophysical characterization of the ETV6 PNT domain polymerization interfaces. Journal of Biological Chemistry 296, 100284. 10.1016/j.jbc.2021.100284. [PDB: 7ju2] CMCF-BM Health
Naineni, Sai Kiran; Liang, Jason; Hull, Kenneth; Cencic, Regina; Zhu, Mingzhao et al. (2021). Functional mimicry revealed by the crystal structure of an eIF4A:RNA complex bound to the interfacial inhibitor, desmethyl pateamine A. Cell Chemical Biology 28(6) . 10.1016/j.chembiol.2020.12.006. [PDB: 6xki] CMCF-ID Health
Chen, Shuo; Wu, Jia-Le; Liang, Ying; Tang, Yi-Gang; Song, Hua-Xin et al. (2021). Arsenic Trioxide Rescues Structural p53 Mutations through a Cryptic Allosteric Site. Cancer Cell 39(2) . 10.1016/j.ccell.2020.11.013. [PDB: 7dhz] CMCF-ID Health