Publication Beamlines Strategic Pillar
Knudson-Goerner, E.J.; Boraston, A.B. (2025). The structure of a family 168 glycoside hydrolase from the marine bacterium Muricauda eckloniae.. Protein Data Bank: 9nhf. CMCF-ID Agriculture
Thomsen, M.; Costanzi, E. (2025). The crystal structure of DNA-bound human MutSbeta (MSH2_E749A/MSH3_E976A) in the canonical mismatch bound conformation with ADP bound in MSH2. Protein Data Bank: 8rb2. CMCF-ID Agriculture
Walker, M.E.; Gu, M.; Lu, J.; Klein, D.J. (2025). E. coli BamA beta-barrel bound to darobactin and cyclic peptide CP2. Protein Data Bank: 9cs1. CMCF-ID Agriculture
Walker, M.E.; Gu, M.; Lu, J.; Klein, D.J. (2025). E. coli BamA beta-barrel bound to darobactin and cyclic peptide CP1. Protein Data Bank: 9cs0. CMCF-ID Agriculture
Deschenes, Natalie M; Pérez-Vargas, Jimena; Zhong, Zoe; Thomas, Merrilee; Kenward, Calem et al. (2025). Functional and Structural Characterization of Treatment-Emergent Nirmatrelvir Resistance Mutations at Low Frequencies in the Main Protease (Mpro) Reveals a Unique Evolutionary Route for SARS-CoV-2 to Gain Resistance. Journal of Infectious Diseases . 10.1093/infdis/jiaf294. [PDB: 9pfh, 9pfi] CMCF-BM Health
Liu, Bin; Yao, Jiangchao; Haimowitz, Thomas; Benetatos, Christopher A.; Boyd, Steven A. et al. (2025). Discovery of VNRX-9945, a Potent, Broadly Active Capsid Assembly Modulator as a Clinical Candidate for the Treatment of Chronic Hepatitis B Virus Infection. ACS Medicinal Chemistry Letters . 10.1021/acsmedchemlett.5c00315. [PDB: 9n3h] CMCF-ID Health
Pemberton, O.A.; Tong, Y.; Nocek, B.; Tang, H.Y.H. (2025). Crystal structure of WRN in complex with compound 43. Protein Data Bank: 9og8. CMCF-ID Health
Tong, Yunsong; Baker, Kenton A.; Chapman, Alex M.; Elsen, Nathaniel L.; Fowler, Faith et al. (2025). Validation, Key Pharmacophores, and X-ray Cocrystal Structures of Novel Biochemically and Cellularly Active WRN Inhibitors Derived from a DNA-Encoded Library Screen. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c03029. [PDB: 9og8] CMCF-ID Health
Knudson-Goerner, Emily; Boraston, Alisdair B. (2025). The structure of a family 168 glycoside hydrolase from the marine bacterium Muricauda eckloniae. Acta Crystallographica Section F:Structural Biology Communications 81(7) . 10.1107/s2053230x2500425x. [PDB: 9nhf] CMCF-ID Health
Krishnan, Shreya S; Shen, Yao; O’Hagan, Treasa B; Matthews, Lindsay A; Weerasinghe, Nuwani W et al. (2025). Asymmetric loading of TnsE regulates Tn7 targeting of DNA replication structures. Nucleic Acids Research 53(11) . 10.1093/nar/gkaf472. [PDB: 9d5l] CMCF-BM Health
Szabla, R.; Junop, M.S.; Wood, K. (2025). Crystal structure of PprA S-F-S tetramer from Deinococcus radiodurans. Protein Data Bank: 9or6. CMCF-ID Health
Mahbub, Luba; Kozlov, Guennadi; Knorn, Caroline; Gehring, Kalle (2025). Structure of the phosphocysteine intermediate of the phosphatase of regenerating liver PTP4A1. Journal of Biological Chemistry , 110251. 10.1016/j.jbc.2025.110251. [PDB: 9mex] CMCF-ID Health
Pau, V.P.T.; Mao, D.Y.L.; Mader, P.; Maderova, Z.; Zimmermann, M. et al. (2025). Crystal structure of PLK4 and RP1664 complex. Protein Data Bank: 9o63. CMCF-ID Health
Vallée, Frédéric; Casás-Selves, Matias; Bubenik, Monica; Duplessis, Martin; Sow, Boubacar et al. (2025). Discovery of RP-1664: A First-in-Class Orally Bioavailable, Selective PLK4 Inhibitor. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.5c00529. [PDB: 9o63] CMCF-ID Health
Frigon, L.; Pascal, J.M. (2025). PARP4 BRCT domain F39A mutant. Protein Data Bank: 9dfr. CMCF-BM Health