| Rahfeld, Peter; Sim, Lyann; Moon, Haisle; Constantinescu, Iren; Morgan-Lang, Connor et al. (2019). An enzymatic pathway in the human gut microbiome that converts A to universal O type blood. Nature Microbiology 4(9) . 10.1038/s41564-019-0469-7. [PDB: 6n1a] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Aggett, Rebecca; Mallette, Evan; Gilbert, Stephanie E.; Vachon, Melody A.; Schroeter, Kurt L. et al. (2019). The steroid side-chain–cleaving aldolase Ltp2–ChsH2DUF35 is a thiolase superfamily member with a radically repurposed active site. Journal of Biological Chemistry 294(31) , jbc.RA119.008889. 10.1074/jbc.ra119.008889. [PDB: 6ok1] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Kimber, M.S.; Mallette, E.; Aggett, R.; Seah, S.Y.K. (2019). Ltp2-ChsH2(DUF35) aldolase. Protein Data Bank: 6ok1. |
CMCF-BM |
PDB Deposition |
Health |
| Newson, JoshuaP.M.; Scott, NichollasE.; Yeuk Wah Chung, Ivy; Wong Fok Lung, Tania; Giogha, Cristina et al. (2019). Salmonella Effectors SseK1 and SseK3 Target Death Domain Proteins in the TNF and TRAIL Signaling Pathways*. Molecular and Cellular Proteomics 18(6) , 1138-1156. 10.1074/mcp.ra118.001093. [PDB: 6cgi, 6dus] |
CMCF-BM, CMCF-ID |
Peer-Reviewed Article |
Health |
| Xu, C.; Boniecki, M.; Cygler, M. (2019). Structure of the N-terminal domain of effector protein SpvB from Salmonella typhimurium strain LT2. Protein Data Bank: 6p0x. |
CMCF-ID |
PDB Deposition |
Health |
| Sim, L.; Rahfeld, P.; Withers, S.G. (2019). Crystal structure of an N-acetylgalactosamine deacetylase from F. plautii in complex with blood group B trisaccharide. Protein Data Bank: 6n1b. |
CMCF-ID |
PDB Deposition |
Health |
| Sim, L.; Rahfeld, P.; Withers, S.G. (2019). Crystal structure of an N-acetylgalactosamine deacetylase from F. plautii. Protein Data Bank: 6n1a. |
CMCF-ID |
PDB Deposition |
Health |
| Kolesnikov, M.; Murphy, M.E.P. (2019). Crystal structure of Fusobacterium nucleatum flavodoxin mutant K13G bound to flavin mononucleotide. Protein Data Bank: 6ohk. |
CMCF-ID |
PDB Deposition |
Health |
| Mothersole, Robert G.; Macdonald, Marta; Kolesnikov, Maxim; Murphy, Michael E. P.; Wolthers, Kirsten R. et al. (2019). Structural insight into the high reduction potentials observed for
Fusobacterium nucleatum
flavodoxin. Protein Science 28(8) . 10.1002/pro.3661. [PDB: 6ohk] |
CMCF-BM |
Peer-Reviewed Article |
Health |
| Shah, M.; Thavalingham, A.; Maxwell, K.L.; Moraes, T.F. (2019). Structure of anti-crispr protein, AcrIIC2. Protein Data Bank: 6n05. |
CMCF-BM |
PDB Deposition |
Health |
| Yachnin, B.J.; Berghuis, A.M. (2019). Crystal structure of trimethoprim-resistant type II dihydrofolate reductase in complex with a bisbenzimidazole inhibitor. Protein Data Bank: 6ny0. |
CMCF-ID |
PDB Deposition |
Health |
| Bryan, Marian C.; Drobnick, Joy; Gobbi, Alberto; Kolesnikov, Aleksandr; Chen, Yongsheng et al. (2019). Development of Potent and Selective Pyrazolopyrimidine IRAK4 Inhibitors. Journal of Medicinal Chemistry 62(13) . 10.1021/acs.jmedchem.9b00439. [PDB: 6o9d] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Yu, C.; Drobnick, J.; Bryan, M.C.; Kiefer, J.; Lupardus, P.J. et al. (2019). Structure of the IRAK4 kinase domain with compound 5. Protein Data Bank: 6o9d. |
CMCF-ID |
PDB Deposition |
Health |
| Sack, J.S. (2019). Crystal structure of JAK3 kinase domain in complex with a pyrrolopyridazine carboxamide inhibitor. Protein Data Bank: 6ny4. |
CMCF-ID |
PDB Deposition |
Health |
| Spergel, Steven H.; Mertzman, Michael E.; Kempson, James; Guo, Junqing; Stachura, Sylwia et al. (2019). Discovery of a JAK1/3 Inhibitor and Use of a Prodrug To Demonstrate Efficacy in a Model of Rheumatoid Arthritis. ACS Medicinal Chemistry Letters 10(3) , 306-311. 10.1021/acsmedchemlett.8b00508. [PDB: 6ny4] |
CMCF-ID |
Peer-Reviewed Article |
Health |