Publication Beamlines Strategic Pillar
Perez-Borrajero, Cecilia; Lin, Chang Sheng-Huei; Okon, Mark; Scheu, Karlton; Graves, Barbara J. et al. (2019). The Biophysical Basis for Phosphorylation-Enhanced DNA-Binding Autoinhibition of the ETS1 Transcription Factor. Journal of Molecular Biology 431(3) . 10.1016/j.jmb.2018.12.011. [PDB: 6da1] CMCF-BM Health
Perez-Bermejo, Juan A.; Efagene, Oghene; Matern, William M.; Holden, Jeffrey K.; Kabir, Shaheen et al. (2024). Functional screening in human HSPCs identifies optimized protein-based enhancers of Homology Directed Repair. Nature Communications 15(1) . 10.1038/s41467-024-46816-5. [PDB: 8svg, 8svh, 8svi] CMCF-ID Health
Penner, Tiffany V.; Cobo, Neil Lorente; Patel, Deepak T.; Patel, Dhruvin H.; Savchenko, Alexei et al. (2023). Structural characterization of the Sel1‐like repeat protein LceB from Legionella pneumophila. Protein Science . 10.1002/pro.4889. [PDB: 8sxq] CMCF-BM Health
Penfield, Jonathan S.; Worrall, Liam J.; Strynadka, Natalie C.; Eltis, Lindsay D. (2014). Substrate Specificities and Conformational Flexibility of 3-Ketosteroid 9α-Hydroxylases. Journal of Biological Chemistry 289(37) , 25523-25536. 10.1074/jbc.m114.575886. [PDB: 4qck, 4qdc, 4qdd, 4qdf] CMCF-BM Health
Peña, Kerry L.; Castel, Stephane E.; de Araujo, Charlotte; Espie, George S.; Kimber, Matthew S. et al. (2010). Structural basis of the oxidative activation of the carboxysomal γ-carbonic anhydrase, CcmM. Proceedings of the National Academy of Sciences of the United States of America 107(6) , 2455-2460. 10.1073/pnas.0910866107. CMCF-ID Health
Pawluk, April; Shah, Megha; Mejdani, Marios; Calmettes, Charles; Moraes, Trevor F. et al. (2017). Disabling a Type I-E CRISPR-Cas Nuclease with a Bacteriophage-Encoded Anti-CRISPR Protein. mBio 8(6) , e01751-17. 10.1128/mbio.01751-17. [PDB: 6arz, 6as4] CMCF-BM Health
Patel, Ankoor; McBride, Jessica A.M.; Mark, Brian L. (2021). The endopeptidase of the maize-affecting Marafivirus type member maize rayado fino virus doubles as a deubiquitinase. Journal of Biological Chemistry 297(2) , 100957. 10.1016/j.jbc.2021.100957. CMCF Health
Partha, Sarathy Karunan; Sadeghi-Khomami, Ali; Slowski, Kathryn; Kotake, Toshihisa; Thomas, Neil R. et al. (2010). Chemoenzymatic Synthesis, Inhibition Studies, and X-ray Crystallographic Analysis of the Phosphono Analog of UDP-Galp as an Inhibitor and Mechanistic Probe for UDP-Galactopyranose Mutase. Journal of Molecular Biology 403(4) , 578-590. 10.1016/j.jmb.2010.08.053. [PDB: 3mj4] CMCF-ID Health
Park, Jaeok; Zielinski, Michal; Magder, Alexandr; Tsantrizos, Youla S.; Berghuis, Albert M. et al. (2017). Human farnesyl pyrophosphate synthase is allosterically inhibited by its own product. Nature Communications 8(1) . 10.1038/ncomms14132. [PDB: 5ja0] CMCF-ID Health
Park, Jaeok; Rodionov, Dmitry; De Schutter, Joris W.; Lin, Yih-Shyan; Tsantrizos, Youla S. et al. (2017). Crystallographic and thermodynamic characterization of phenylaminopyridine bisphosphonates binding to human farnesyl pyrophosphate synthase. PLoS ONE 12(10) , e0186447. 10.1371/journal.pone.0186447. [PDB: 4nfi, 4nfj, 4nfk] CMCF-ID Health
Park, Jaeok; Lin, Yih-Shyan; Tsantrizos, Youla S.; Berghuis, Albert M. (2014). Structure of human farnesyl pyrophosphate synthase in complex with an aminopyridine bisphosphonate and two molecules of inorganic phosphate. Acta Crystallographica Section F Structural Biology and Crystallization Communications 70(3) , 299-304. 10.1107/s2053230x14002106. [PDB: 4lfv] CMCF-ID Health
Park, Jaeok; Leung, Chun Yuen; Matralis, Alexios N.; Lacbay, Cyrus M.; Tsakos, Michail et al. (2017). Pharmacophore Mapping of Thienopyrimidine-Based Monophosphonate (ThP-MP) Inhibitors of the Human Farnesyl Pyrophosphate Synthase. Journal of Medicinal Chemistry 60(5) , 2119-2134. 10.1021/acs.jmedchem.6b01888. [PDB: 5juz, 5jv1] CMCF-ID Health
Parker, Michelle L.; Penarete-Vargas, Diana M.; Hamilton, Phineas T.; Guérin, Amandine; Dubey, Jitender P. et al. (2015). Dissecting the interface between apicomplexan parasite and host cell: Insights from a divergent AMA–RON2 pair. Proceedings of the National Academy of Sciences of the United States of America 113(2) , 398-403. 10.1073/pnas.1515898113. [PDB: 4z80, 4z81] CMCF-ID Health
Parker, Michelle L.; Houston, Simon; Wetherell, Charmaine; Cameron, Caroline E.; Boulanger, Martin J. et al. (2016). The Structure of Treponema pallidum Tp0624 Reveals a Modular Assembly of Divergently Functionalized and Previously Uncharacterized Domains. PLoS ONE 11(11) , e0166274. 10.1371/journal.pone.0166274. [PDB: 5jir] CMCF-ID Health
Parker, Michelle L.; Houston, Simon; Pětrošová, Helena; Lithgow, Karen V.; Hof, Rebecca et al. (2016). The Structure of Treponema pallidum Tp0751 (Pallilysin) Reveals a Non-canonical Lipocalin Fold That Mediates Adhesion to Extracellular Matrix Components and Interactions with Host Cells. PLoS Pathogens 12(9) , e1005919. 10.1371/journal.ppat.1005919. [PDB: 5jk2] CMCF-ID Health