Publication Beamlines Strategic Pillar
Awad, Mark M.; Katayama, Ryohei; McTigue, Michele; Liu, Wei; Deng, Ya-Li et al. (2013). Acquired Resistance to Crizotinib from a Mutation in CD74–ROS1. New England Journal of Medicine 368(25) , 2395-2401. 10.1056/nejmoa1215530. [PDB: 3zbf] CMCF-ID Health
Axerio-Cilies, Peter; See, Raymond H; Zoraghi, Roya; Worral, Liam; Lian, Tian et al. (2011). Cheminformatics-Driven Discovery of Selective, Nanomolar Inhibitors for Staphylococcal Pyruvate Kinase. ACS Chemical Biology 7(2) , 350-359. 10.1021/cb2003576. [PDB: 3t0t] CMCF-ID Health
Aydin, Halil; Smrke, Brianna M.; Lee, Jeffrey E. (2013). Structural characterization of a fusion glycoprotein from a retrovirus that undergoes a hybrid 2‐step entry mechanism. FASEB Journal 27(12) , 5059-5071. 10.1096/fj.13-232371. [PDB: 5h9c] CMCF-ID Health
Aydin, Halil; Sultana, Azmiri; Li, Sheng; Thavalingam, Annoj; Lee, Jeffrey E. et al. (2016). Molecular architecture of the human sperm IZUMO1 and egg JUNO fertilization complex. Nature 534(7608) , 562-565. 10.1038/nature18595. [PDB: 5f4e, 5f4t, 5f4v] CMCF-ID Health
Azoitei, Mihai L.; Ban, Yih-En Andrew; Julien, Jean-Philippe; Bryson, Steve; Schroeter, Alexandria et al. (2012). Computational Design of High-Affinity Epitope Scaffolds by Backbone Grafting of a Linear Epitope. Journal of Molecular Biology 415(1) , 175-192. 10.1016/j.jmb.2011.10.003. [PDB: 3rhu] CMCF-ID Health
Bacik, John-Paul; Klesmith, Justin R.; Whitehead, Timothy A.; Jarboe, Laura R.; Unkefer, Clifford J. et al. (2015). Producing Glucose 6-Phosphate from Cellulosic Biomass. Journal of Biological Chemistry 290(44) , 26638-26648. 10.1074/jbc.m115.674614. [PDB: 4yh5, 4zfv, 4zlu, 5bsb] CMCF-ID Agriculture
Bacik, John-Paul; Tavassoli, Marjan; Patel, Trushar R.; McKenna, Sean A.; Vocadlo, David J. et al. (2014). Conformational Itinerary of Pseudomonas aeruginosa 1,6-Anhydro-N-acetylmuramic Acid Kinase during Its Catalytic Cycle. Journal of Biological Chemistry 289(7) , 4504-4514. 10.1074/jbc.m113.521633. [PDB: 4mo4, 4mo5] CMCF-ID Health
Bacik, John-Paul; Whitworth, Garrett E.; Stubbs, Keith A.; Vocadlo, David J.; Mark, Brian L. et al. (2012). Active Site Plasticity within the Glycoside Hydrolase NagZ Underlies a Dynamic Mechanism of Substrate Distortion. Chemistry & Biology 19(11) , 1471-1482. 10.1016/j.chembiol.2012.09.016. [PDB: 4gvf, 4gvg, 4gvh, 4gyj, 4gyk] CMCF-ID Health
Bacik, John-Paul; Whitworth, Garrett E.; Stubbs, Keith A.; Yadav, Anuj K.; Martin, Dylan R. et al. (2011). Molecular Basis of 1,6-Anhydro Bond Cleavage and Phosphoryl Transfer by Pseudomonas aeruginosa 1,6-Anhydro-N-acetylmuramic Acid Kinase. Journal of Biological Chemistry 286(14) , 12283-12291. 10.1074/jbc.m110.198317. [PDB: 3qbw, 3qbx] CMCF-ID Health
Badea, Ildiko; Poorghorban, Masoomeh; Das, Umashankar; Alaidi, Osama; Chitanda, Jackson et al. (2015). Characterization of the host–guest complex of a curcumin analog with β-cyclodextrin and β-cyclodextrin–gemini surfactant and evaluation of its anticancer activity. International Journal of Nanomedicine , 503-515. 10.2147/ijn.s70828. CMCF-BM, MID-IR Health
Bagal, Sharan K.; Andrews, Mark; Bechle, Bruce M.; Bian, Jianwei; Bilsland, James et al. (2018). Discovery of Potent, Selective, and Peripherally Restricted Pan-Trk Kinase Inhibitors for the Treatment of Pain. Journal of Medicinal Chemistry 61(15) , 6779-6800. 10.1021/acs.jmedchem.8b00633. [PDB: 6dkb] CMCF-ID Health
Bagal, Sharan K.; Omoto, Kiyoyuki; Blakemore, David C.; Bungay, Peter J.; Bilsland, James G. et al. (2018). Discovery of Allosteric, Potent, Subtype Selective, and Peripherally Restricted TrkA Kinase Inhibitors. Journal of Medicinal Chemistry 62(1) , 247-265. 10.1021/acs.jmedchem.8b00280. [PDB: 6d20] CMCF-ID Health
Bai, Bing; Belovodskiy, Alexandr; Hena, Mostofa; Kandadai, Appan Srinivas; Joyce, Michael A. et al. (2021). Peptidomimetic α-Acyloxymethylketone Warheads with Six-Membered Lactam P1 Glutamine Mimic: SARS-CoV-2 3CL Protease Inhibition, Coronavirus Antiviral Activity, and in Vitro Biological Stability. Journal of Medicinal Chemistry 65(4) . 10.1021/acs.jmedchem.1c00616. CMCF-BM Health
Bailey-Elkin, Ben A.; Knaap, Robert C. M.; De Silva, Anuradha; Boekhoud, Ilse M.; Mous, Sandra et al. (2023). Demonstrating the importance of porcine reproductive and respiratory syndrome virus papain-like protease 2 deubiquitinating activity in viral replication by structure-guided mutagenesis. PLoS Pathogens 19(12) , e1011872. 10.1371/journal.ppat.1011872. [PDB: 8ehn] CMCF-ID Health
Bailey-Elkin, Ben A.; Knaap, Robert C.M.; Johnson, Garrett G.; Dalebout, Tim J.; Ninaber, Dennis K. et al. (2014). Crystal Structure of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Papain-like Protease Bound to Ubiquitin Facilitates Targeted Disruption of Deubiquitinating Activity to Demonstrate Its Role in Innate Immune Suppression. Journal of Biological Chemistry 289(50) , 34667-34682. 10.1074/jbc.m114.609644. [PDB: 4rez, 4rf0, 4rf1] CMCF-BM Health