Publication Beamlines Strategic Pillar
Jha, Vikash; Ling, Hong (2018). Structural Basis for Human DNA Polymerase Kappa to Bypass Cisplatin Intrastrand Cross-Link (Pt-GG) Lesion as an Efficient and Accurate Extender. Journal of Molecular Biology 430(11) , 1577-1589. 10.1016/j.jmb.2018.04.023. [PDB: 6brx, 6bs1] CMCF-ID Health
Jha, Vikash; Ling, Hong (2017). Structural basis of accurate replication beyond a bulky major benzo[a]pyrene adduct by human DNA polymerase kappa. DNA Repair 49, 43-50. 10.1016/j.dnarep.2016.11.001. [PDB: 5t14] CMCF-ID Health
Jha, Vikash; Louis, Sherif; Chelikani, Prashen; Carpena, Xavi; Donald, Lynda J. et al. (2011). Modulation of Heme Orientation and Binding by a Single Residue in Catalase HPII of Escherichia coli. Biochemistry 50(12) , 2101-2110. 10.1021/bi200027v. [PDB: 3p9p, 3p9q, 3p9r, 3p9s, 3pq2, 3pq3, 3pq4, 3pq5, 3pq6, 3pq7, 3pq8] CMCF-ID Health
Johal, A. R.; Blackler, R. J.; Alfaro, J. A.; Schuman, B.; Borisova, S. et al. (2013). pH-induced conformational changes in human ABO(H) blood group glycosyltransferases confirm the importance of electrostatic interactions in the formation of the semi-closed state. Glycobiology 24(3) , 237-246. 10.1093/glycob/cwt098. [PDB: 4fre, 4frh, 4frl, 4frm, 4fro, 4frp, 4frq] CMCF-ID Health
Johnson, Ted W.; Richardson, Paul F.; Bailey, Simon; Brooun, Alexei; Burke, Benjamin J. et al. (2014). Discovery of (10R)-7-Amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile (PF-06463922), a Macrocyclic Inhibitor of Anaplastic Lymphoma Kinase (ALK) and c-ros Oncogene 1 (ROS1) with Preclinical Brain Exposure and Broad-Spectrum Potency against ALK-Resistant Mutations. Journal of Medicinal Chemistry 57(11) , 4720-4744. 10.1021/jm500261q. [PDB: 4ctb] CMCF-ID Health
Johnson, Troy A.; Mcleod, Matthew J.; Holyoak, Todd (2016). Utilization of Substrate Intrinsic Binding Energy for Conformational Change and Catalytic Function in Phosphoenolpyruvate Carboxykinase. Biochemistry 55(3) , 575-587. 10.1021/acs.biochem.5b01215. [PDB: 5fh0, 5fh1, 5fh2] CMCF-ID Health
Jones, Carys S.; Sychantha, David; Howell, P. Lynne; Clarke, Anthony J. (2020). Structural basis for the O-acetyltransferase function of the extracytoplasmic domain of OatA from Staphylococcus aureus. Journal of Biological Chemistry 295(24) , jbc.RA120.013108. 10.1074/jbc.ra120.013108. [PDB: 6wn9] CMCF-BM Health
Jones, Darryl R.; McLean, Richard; Hobbs, Joanne K.; Abbott, D. Wade (2019). A surrogate structural platform informed by ancestral reconstruction and resurrection of a putative carbohydrate binding module hybrid illuminates the neofunctionalization of a pectate lyase. Journal of Structural Biology 207(3) , 279-286. 10.1016/j.jsb.2019.06.003. [PDB: 6ojk, 6ojl] CMCF-ID Health
Jones, Darryl R.; Xing, Xiaohui; Tingley, Jeffrey P.; Klassen, Leeann; King, Marissa L. et al. (2020). Analysis of Active Site Architecture and Reaction Product Linkage Chemistry Reveals a Conserved Cleavage Substrate for an Endo-alpha-mannanase within Diverse Yeast Mannans. Journal of Molecular Biology 432(4) , 1083-1097. 10.1016/j.jmb.2019.12.048. [PDB: 6u4z] CMCF-BM Agriculture
Jones, Michael D.; Chan, Anson C. K.; Nomellini, John F.; Murphy, Michael E. P.; Smit, John et al. (2016). Surface-layer protein fromCaulobacter crescentus: expression, purification and X-ray crystallographic analysis. Acta Crystallographica Section F:Structural Biology Communications 72(9) , 677-680. 10.1107/s2053230x16011638. CMCF-ID Health
Jørgensen, René; Wang, Yolanda; Visschedyk, Danielle; Merrill, A Rod (2008). The nature and character of the transition state for the ADP‐ribosyltransferase reaction. EMBO Reports 9(8) , 802-809. 10.1038/embor.2008.90. [PDB: 2zit] CMCF-ID Health
Juang, Yu-Chi; Landry, Marie-Claude; Sanches, Mario; Vittal, Vinayak; Leung, Charles C.Y. et al. (2012). OTUB1 Co-opts Lys48-Linked Ubiquitin Recognition to Suppress E2 Enzyme Function. Molecular Cell 45(3) , 384-397. 10.1016/j.molcel.2012.01.011. [PDB: 4ddg] CMCF-ID Health
Julien, Jean-Philippe; Cupo, Albert; Sok, Devin; Stanfield, Robyn L.; Lyumkis, Dmitry et al. (2013). Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer. Science 342(6165) , 1477-1483. 10.1126/science.1245625. CMCF-BM, CMCF-ID Health
Julien, Jean-Philippe; Cupo, Albert; Sok, Devin; Stanfield, Robyn L.; Lyumkis, Dmitry et al. (2013). Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer. Science 342(6165) , 1477-1483. 10.1126/science.1245625. CMCF-BM, CMCF-ID Health
Juvvadi, Praveen R.; Fox, David; Bobay, Benjamin G.; Hoy, Michael J.; Gobeil, Sophie M. C. et al. (2019). Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents. Nature Communications 10(1) . 10.1038/s41467-019-12199-1. [PDB: 6tz7] CMCF-ID Health