Publication Beamlines Strategic Pillar
Michino, Mayako; Beautrait, Alexandre; Boyles, Nicholas A.; Nadupalli, Aparna; Dementiev, Alexey et al. (2023). Shape-Based Virtual Screening of a Billion-Compound Library Identifies Mycobacterial Lipoamide Dehydrogenase Inhibitors. ACS Bio and Med Chem Au 3(6) , 507-515. 10.1021/acsbiomedchemau.3c00046. [PDB: 8u0q] CMCF-ID Health
Meza-Avina, Maria Elena; Wei, Lianhu; Liu, Yan; Poduch, Ewa; Bello, Angelica M. et al. (2010). Structural determinants for the inhibitory ligands of orotidine-5′-monophosphate decarboxylase. Bioorganic and Medicinal Chemistry 18(11) , 4032-4041. 10.1016/j.bmc.2010.04.017. [PDB: 3mi2] CMCF-ID Health
Methot, Joey L.; Zhou, Hua; Kattar, Sam D.; McGowan, Meredeth A.; Wilson, Kevin et al. (2019). Structure Overhaul Affords a Potent Purine PI3Kδ Inhibitor with Improved Tolerability. Journal of Medicinal Chemistry 62(9) . 10.1021/acs.jmedchem.8b01818. [PDB: 6mul] CMCF-ID Health
Mendoza, Matthew N.; Jian, Mike; King, Moeko T.; Brooks, Cory L. (2020). Role of a noncanonical disulfide bond in the stability, affinity, and flexibility of a VHH specific for the Listeria virulence factor InlB. Protein Science 29(4) , 1004-1017. 10.1002/pro.3831. [PDB: 6u12, 6u14] CMCF-ID Health
Mendez, Alex; Bolling, Cydni; Taylor, Shane; Makumire, Stanley; Staker, Bart et al. (2025). Structure of Plasmodium vivax N-myristoyltransferase with inhibitor IMP-1088: exploring an NMT inhibitor for antimalarial therapy. Acta Crystallographica Section F:Structural Biology Communications 81(1) , 1-10. 10.1107/s2053230x24011348. [PDB: 5v0w] CMCF-ID Health
Mellor, Paul; Marshall, Jeremy D. S.; Ruan, Xuan; Whitecross, Dielle E.; Ross, Rebecca L. et al. (2018). Patient-derived mutations within the N-terminal domains of p85α impact PTEN or Rab5 binding and regulation. Scientific Reports 8(1) . 10.1038/s41598-018-25487-5. [PDB: 6d81, 6d82, 6d85, 6d86, 6d87] CMCF-BM, CMCF-ID Health
Mellor, Paul; Marshall, Jeremy D. S.; Ruan, Xuan; Whitecross, Dielle E.; Ross, Rebecca L. et al. (2018). Patient-derived mutations within the N-terminal domains of p85α impact PTEN or Rab5 binding and regulation. Scientific Reports 8(1) . 10.1038/s41598-018-25487-5. [PDB: 6d81, 6d82, 6d85, 6d86, 6d87] CMCF-BM, CMCF-ID Health
McPhail, Jacob A.; Ottosen, Erik H.; Jenkins, Meredith L.; Burke, John E. (2017). The Molecular Basis of Aichi Virus 3A Protein Activation of Phosphatidylinositol 4 Kinase IIIβ, PI4KB, through ACBD3. Structure 25(1) , 121-131. 10.1016/j.str.2016.11.016. [PDB: 5tdq] CMCF-ID Health
McLeod, Matthew J.; Tran, Norman; McCluskey, Gregory D.; Gillis, Tom D.; Bearne, Stephen L. et al. (2023). A metal‐dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine‐5′‐triphosphate. Protein Science 32(6) . 10.1002/pro.4648. [PDB: 8fv6, 8fv7, 8fv8, 8fv9, 8fva, 8fvb] CMCF-BM Health
Mcleod, Matthew J.; Krismanich, Anthony P.; Assoud, Abdeljalil; Dmitrienko, Gary I.; Holyoak, Todd et al. (2019). Characterization of 3-[(Carboxymethyl)thio]picolinic Acid: A Novel Inhibitor of Phosphoenolpyruvate Carboxykinase. Biochemistry 58(37) , 3918-3926. 10.1021/acs.biochem.9b00583. [PDB: 6p5o] CMCF-ID Health
McLeod, Matthew J.; Holyoak, Todd (2023). Biochemical, structural, and kinetic characterization of PPi‐dependent phosphoenolpyruvate carboxykinase from Propionibacterium freudenreichii. Proteins: Structure. Function and Bioinformatics . 10.1002/prot.26513. [PDB: 8e1u] CMCF-BM Health
McLeod, Brandon; Miura, Kazutoyo; Scally, Stephen W.; Bosch, Alexandre; Nguyen, Ngan et al. (2019). Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25. Nature Communications 10(1) . 10.1038/s41467-019-11980-6. [PDB: 6phb, 6phc, 6phd, 6phf, 6phg, 6phh] CMCF-ID Health
McGurn, Leah D.; Moazami-Goudarzi, Maryam; White, Sean A.; Suwal, Tannu; Brar, Beant et al. (2016). The structure, kinetics and interactions of the β-carboxysomal β-carbonic anhydrase, CcaA. Biochemical Journal 473(24) , 4559-4572. 10.1042/bcj20160773. [PDB: 5swc] CMCF-ID Health
McGregor, Nicholas; Yin, Victor; Tung, Ching‐Chieh; Van Petegem, Filip; Brumer, Harry et al. (2017). Crystallographic insight into the evolutionary origins of xyloglucan endotransglycosylases and endohydrolases. Plant Journal 89(4) , 651-670. 10.1111/tpj.13421. [PDB: 5dze, 5dzf, 5sv8] CMCF-ID Agriculture
McGregor, Alexandra K.; Chan, Anson C.K.; Schroeder, Megan D.; Do, Long T.M.; Saini, Gurpreet et al. (2023). A new member of the flavodoxin superfamily from Fusobacterium nucleatum that functions in heme trafficking and reduction of anaerobilin. Journal of Biological Chemistry 299(7) , 104902. 10.1016/j.jbc.2023.104902. [PDB: 8g64] CMCF-BM Health