Publication Beamlines Strategic Pillar
Wahba, Haytham M.; Lecoq, Lauriane; Stevenson, Michael; Mansour, Ahmed; Cappadocia, Laurent et al. (2016). Structural and Biochemical Characterization of a Copper-Binding Mutant of the Organomercurial Lyase MerB: Insight into the Key Role of the Active Site Aspartic Acid in Hg–Carbon Bond Cleavage and Metal Binding Specificity. Biochemistry 55(7) , 1070-1081. 10.1021/acs.biochem.5b01298. [PDB: 5c17] CMCF-ID Environment
Wagner, Florence F.; Benajiba, Lina; Campbell, Arthur J.; Weïwer, Michel; Sacher, Joshua R. et al. (2018). Exploiting an Asp-Glu “switch” in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia. Science Translational Medicine 10(431) , eaam8460. 10.1126/scitranslmed.aam8460. [PDB: 5kpl, 5kpm] CMCF-ID Health
Vuong, Wayne; Fischer, Conrad; Khan, Muhammad Bashir; van Belkum, Marco J.; Lamer, Tess et al. (2021). Improved SARS-CoV-2 Mpro inhibitors based on feline antiviral drug GC376: Structural enhancements, increased solubility, and micellar studies. European Journal of Medicinal Chemistry 222, 113584. 10.1016/j.ejmech.2021.113584. [PDB: 7lco, 7ldl] CMCF-BM Health
Vu, Binh T.; Dominique, Romyr; Fahr, Bruce J.; Li, Hongju H.; Fry, David C. et al. (2024). Discovery of Rezatapopt (PC14586), a First-in-Class, Small-Molecule Reactivator of p53 Y220C Mutant in Development. ACS Medicinal Chemistry Letters . 10.1021/acsmedchemlett.4c00379. [PDB: 9br4] CMCF-ID Health
Voth, Kevin; Pasricha, Shivani; Chung, Ivy Yeuk Wah; Wibawa, Rachelia R.; Zainudin, Engku Nuraishah Huda E. et al. (2021). Structural and Functional Characterization of Legionella pneumophila Effector MavL. Biomolecules 11(12) , 1802. 10.3390/biom11121802. CMCF-ID Health
Voth, Kevin A.; Chung, Ivy Yeuk Wah; Straaten, Karin; Li, Lei; Boniecki, Michal T. et al. (2018). The structure of Legionella effector protein LpnE provides insights into its interaction with Oculocerebrorenal syndrome of Lowe ( OCRL ) protein. FEBS Journal 286(4) , 710-725. 10.1111/febs.14710. [PDB: 6deh] CMCF-ID Health
Von Kreudenstein, Thomas Spreter; Escobar-Carbrera, Eric; Lario, Paula I.; D’Angelo, Igor; Brault, Karine et al. (2013). Improving biophysical properties of a bispecific antibody scaffold to aid developability. mAbs 5(5) , 646-654. 10.4161/mabs.25632. [PDB: 4bsv, 4bsw] CMCF-BM Health
Von Dwingelo, Juanita; Chung, Ivy Yeuk Wah; Price, Christopher T.; Li, Lei; Jones, Snake et al. (2019). Interaction of the Ankyrin H Core Effector of Legionella with the Host LARP7 Component of the 7SK snRNP Complex. mBio 10(4) , e01942-19. 10.1128/mbio.01942-19. [PDB: 6mca] CMCF-BM, CMCF-ID Health
Von Dwingelo, Juanita; Chung, Ivy Yeuk Wah; Price, Christopher T.; Li, Lei; Jones, Snake et al. (2019). Interaction of the Ankyrin H Core Effector of Legionella with the Host LARP7 Component of the 7SK snRNP Complex. mBio 10(4) , e01942-19. 10.1128/mbio.01942-19. [PDB: 6mca] CMCF-BM, CMCF-ID Health
Volkers, Gesa; Worrall, Liam J; Kwan, David H; Yu, Ching-Ching; Baumann, Lars et al. (2015). Structure of human ST8SiaIII sialyltransferase provides insight into cell-surface polysialylation. Nature Structural and Molecular Biology 22(8) , 627-635. 10.1038/nsmb.3060. [PDB: 5bo6, 5bo7, 5bo8] CMCF-BM, CMCF-ID Health
Volkers, Gesa; Worrall, Liam J; Kwan, David H; Yu, Ching-Ching; Baumann, Lars et al. (2015). Structure of human ST8SiaIII sialyltransferase provides insight into cell-surface polysialylation. Nature Structural and Molecular Biology 22(8) , 627-635. 10.1038/nsmb.3060. [PDB: 5bo6, 5bo7, 5bo8] CMCF-BM, CMCF-ID Health
Visschedyk, Danielle; Rochon, Amanda; Tempel, Wolfram; Dimov, Svetoslav; Park, Hee-Won et al. (2012). Certhrax Toxin, an Anthrax-related ADP-ribosyltransferase from Bacillus cereus. Journal of Biological Chemistry 287(49) , 41089-41102. 10.1074/jbc.m112.412809. [PDB: 4fxq, 4gf1] CMCF-ID Health
Vinogradova, Maia; Gehling, Victor S; Gustafson, Amy; Arora, Shilpi; Tindell, Charles A et al. (2016). An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells. Nature Chemical Biology 12(7) , 531-538. 10.1038/nchembio.2085. [PDB: 5ceh] CMCF-ID Health
Vinaik, Roohi; Kozlov, Guennadi; Gehring, Kalle (2013). Structure of the Non-Catalytic Domain of the Protein Disulfide Isomerase-Related Protein (PDIR) Reveals Function in Protein Binding. PLoS ONE 8(4) , e62021. 10.1371/journal.pone.0062021. CMCF-ID Health
Vidossich, Pietro; Loewen, Peter C.; Carpena, Xavi; Fiorin, Giacomo; Fita, Ignacio et al. (2014). Binding of the Antitubercular Pro-Drug Isoniazid in the Heme Access Channel of Catalase-Peroxidase (KatG). A Combined Structural and Metadynamics Investigation. Journal of Physical Chemistry B 118(11) , 2924-2931. 10.1021/jp4123425. [PDB: 5syi] CMCF-ID Health