Publication Beamlines Strategic Pillar
Holt, Christian; Hamborg, Louise; Lau, Kelvin; Brohus, Malene; Sørensen, Anders Bundgaard et al. (2020). The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor. Journal of Biological Chemistry 295(22) , jbc.RA120.013430. 10.1074/jbc.ra120.013430. [PDB: 6y4p] CMCF-BM Health
Hogan, David T.; Gelfand, Benjamin S.; Spasyuk, Denis M.; Sutherland, Todd C. (2020). Subtle substitution controls the rainbow chromatic behaviour of multi-stimuli responsive core-expanded pyrenes. Materials Chemistry Frontiers 4(1) , 268-276. 10.1039/c9qm00710e. CMCF-BM Materials
Hodge, Curtis D.; Edwards, Ross A.; Markin, Craig J.; McDonald, Darin; Pulvino, Mary et al. (2015). Covalent Inhibition of Ubc13 Affects Ubiquitin Signaling and Reveals Active Site Elements Important for Targeting. ACS Chemical Biology 10(7) , 1718-1728. 10.1021/acschembio.5b00222. [PDB: 4onm, 4onn] CMCF-BM Health
Hobbs, Joanne K.; Pluvinage, Benjamin; Robb, Melissa; Smith, Steven P.; Boraston, Alisdair B. et al. (2019). Two complementary α-fucosidases from Streptococcus pneumoniae promote complete degradation of host-derived carbohydrate antigens. Journal of Biological Chemistry 294(34) , jbc.RA119.009368. 10.1074/jbc.ra119.009368. [PDB: 6or4] CMCF-BM, CMCF-ID Health
Hobbs, Joanne K.; Lee, Seunghyae M.; Robb, Melissa; Hof, Fraser; Barr, Christopher et al. (2016). KdgF, the missing link in the microbial metabolism of uronate sugars from pectin and alginate. Proceedings of the National Academy of Sciences of the United States of America 113(22) , 6188-6193. 10.1073/pnas.1524214113. [PDB: 5fpx, 5fpz] CMCF-ID Materials
Hill, Matthew D.; Quesnelle, Claude; Tokarski, John; Fang, Haiquan; Fanslau, Carolynn et al. (2021). Development of BET inhibitors as potential treatments for cancer: A new carboline chemotype. Bioorganic and Medicinal Chemistry Letters 51, 128376. 10.1016/j.bmcl.2021.128376. [PDB: 7mce] CMCF-ID Health
Hilger, David M.; Hamilton, Jordan G.; Peak, Derek (2020). The Influences of Magnesium upon Calcium Phosphate Mineral Formation and Structure as Monitored by X-ray and Vibrational Spectroscopy. Soil Systems 4(1) , 8. 10.3390/soilsystems4010008. CMCF-BM, SXRMB Environment
Higgins, Melanie A.; Whitworth, Garrett E.; El Warry, Nahida; Randriantsoa, Mialy; Samain, Eric et al. (2009). Differential Recognition and Hydrolysis of Host Carbohydrate Antigens by Streptococcus pneumoniae Family 98 Glycoside Hydrolases. Journal of Biological Chemistry 284(38) , 26161-26173. 10.1074/jbc.m109.024067. CMCF-ID Health
Higgins, Melanie A.; Tegl, Gregor; MacDonald, Spencer S.; Arnal, Gregory; Brumer, Harry et al. (2021). N-Glycan Degradation Pathways in Gut- and Soil-Dwelling Actinobacteria Share Common Core Genes. ACS Chemical Biology 16(4) . 10.1021/acschembio.0c00995. [PDB: 7lqx, 7lr1] CMCF-ID Health
Higgins, Melanie A.; Suits, Michael D.; Marsters, Candace; Boraston, Alisdair B. (2014). Structural and Functional Analysis of Fucose-Processing Enzymes from Streptococcus pneumoniae. Journal of Molecular Biology 426(7) , 1469-1482. 10.1016/j.jmb.2013.12.006. [PDB: 4c21, 4c22] CMCF-BM Health
Higgins, Melanie A.; Ficko-Blean, Elizabeth; Meloncelli, Peter J.; Lowary, Todd L.; Boraston, Alisdair B. et al. (2011). The Overall Architecture and Receptor Binding of Pneumococcal Carbohydrate-Antigen-Hydrolyzing Enzymes. Journal of Molecular Biology 411(5) , 1017-1036. 10.1016/j.jmb.2011.06.035. [PDB: 2ygm] CMCF-ID Health
He, Yang; Ning, Tingting; Xie, Tingting; Qiu, Qingchuan; Zhang, Liping et al. (2011). Large-scale production of functional human serum albumin from transgenic rice seeds. Proceedings of the National Academy of Sciences of the United States of America 108(47) , 19078-19083. 10.1073/pnas.1109736108. [PDB: 3sqj] CMCF-ID Health
He, Xiao; Szewczyk, Paul; Karyakin, Andrey; Evin, Mariah; Hong, Wen-Xu et al. (2010). Structure of a cation-bound multidrug and toxic compound extrusion transporter. Nature 467(7318) , 991-994. 10.1038/nature09408. CMCF-ID Health
Hewitt, Stephen N.; Choi, Ryan; Kelley, Angela; Crowther, Gregory J.; Napuli, Alberto J. et al. (2011). Expression of proteins inEscherichia colias fusions with maltose-binding protein to rescue non-expressed targets in a high-throughput protein-expression and purification pipeline. Acta Crystallographica Section F Structural Biology and Crystallization Communications 67(9) , 1006-1009. 10.1107/s1744309111022159. [PDB: 3u40] CMCF-ID Health
Hewitt, Stephen Nakazawa; Dranow, David M.; Horst, Benjamin G.; Abendroth, Jan A.; Forte, Barbara et al. (2016). Biochemical and Structural Characterization of Selective Allosteric Inhibitors of the Plasmodium falciparum Drug Target, Prolyl-tRNA-synthetase. ACS Infectious Diseases 3(1) , 34-44. 10.1021/acsinfecdis.6b00078. [PDB: 4wi1, 5ifu] CMCF-ID Health