Publication Beamlines Strategic Pillar
Fodje, Michel; Mundboth, Kiran; Labiuk, Shaunivan; Janzen, Kathryn; Gorin, James et al. (2020). Macromolecular crystallography beamlines at the Canadian Light Source: building on success. Acta Crystallographica Section D: Structural Biology 76(7) . 10.1107/s2059798320007603. CMCF-BM, CMCF-ID Health
Fieldhouse, Robert J.; Jørgensen, René; Lugo, Miguel R.; Merrill, A. Rod (2012). The 1.8 Å Cholix Toxin Crystal Structure in Complex with NAD+ and Evidence for a New Kinetic Model. Journal of Biological Chemistry 287(25) , 21176-21188. 10.1074/jbc.m111.337311. [PDB: 3q9o] CMCF-ID Health
Ficko-Blean, Elizabeth; Stuart, Christopher P.; Boraston, Alisdair B. (2011). Structural analysis of CPF_2247, a novel α-amylase from Clostridium perfringens. Proteins: Structure. Function and Bioinformatics 79(10) , 2771-2777. 10.1002/prot.23116. [PDB: 3ren] CMCF-ID Health
Ferri, Elena; Le Thomas, Adrien; Wallweber, Heidi Ackerly; Day, Eric S.; Walters, Benjamin T. et al. (2020). Activation of the IRE1 RNase through remodeling of the kinase front pocket by ATP-competitive ligands. Nature Communications 11(1) . 10.1038/s41467-020-19974-5. [PDB: 6w3b, 6w3c] CMCF-ID Health
Feng, Yuting; Park, Jaeok; Li, Shi-Guang; Boutin, Rebecca; Viereck, Peter et al. (2019). Chirality-Driven Mode of Binding of α-Aminophosphonic Acid-Based Allosteric Inhibitors of the Human Farnesyl Pyrophosphate Synthase (hFPPS). Journal of Medicinal Chemistry 62(21) , 9691-9702. 10.1021/acs.jmedchem.9b01104. [PDB: 6n7y, 6n82, 6n83, 6oag, 6oah] CMCF-BM, CMCF-ID Health
Fedoretz-Maxwell, Brooklyn P.; Shin, Catherine H.; MacNeil, Gregory A.; Worrall, Liam J.; Park, Rachel et al. (2022). The Impact of Second Coordination Sphere Methionine-Aromatic Interactions in Copper Proteins. Inorganic Chemistry 61(14) , 5563-5571. 10.1021/acs.inorgchem.2c00030. [PDB: 7tc5] CMCF-BM, CMCF-ID Health
Farha, Maya A.; Czarny, Tomasz L.; Myers, Cullen L.; Worrall, Liam J.; French, Shawn et al. (2015). Antagonism screen for inhibitors of bacterial cell wall biogenesis uncovers an inhibitor of undecaprenyl diphosphate synthase. Proceedings of the National Academy of Sciences of the United States of America 112(35) , 11048-11053. 10.1073/pnas.1511751112. [PDB: 5cqb, 5cqj] CMCF-ID Health
Ezekiel, Sean J.; Searle, Mackenzie; Park, Jaeok (2025). Engineering dimer mutants of human geranylgeranyl pyrophosphate synthase. PLoS ONE 20(1) , e0317437. 10.1371/journal.pone.0317437. [PDB: 9csl] CMCF-ID Health
Ernst, Andreas; Avvakumov, George; Tong, Jiefei; Fan, Yihui; Zhao, Yanling et al. (2013). A Strategy for Modulation of Enzymes in the Ubiquitin System. Science 339(6119) , 590-595. 10.1126/science.1230161. [PDB: 3n3k] CMCF-ID Health
Ereño-Orbea, June; Sicard, Taylor; Cui, Hong; Mazhab-Jafari, Mohammad T.; Benlekbir, Samir et al. (2017). Molecular basis of human CD22 function and therapeutic targeting. Nature Communications 8(1) . 10.1038/s41467-017-00836-6. [PDB: 5vkj, 5vkk, 5vkm, 5vl3] CMCF-BM, CMCF-ID Health
Ereño-Orbea, June; Sicard, Taylor; Cui, Hong; Carson, Jacob; Hermans, Pim et al. (2018). Structural Basis of Enhanced Crystallizability Induced by a Molecular Chaperone for Antibody Antigen-Binding Fragments. Journal of Molecular Biology 430(3) , 322-336. 10.1016/j.jmb.2017.12.010. [PDB: 6ana, 6and, 6ani] CMCF-ID Health
Ereño-Orbea, June; Liu, Xianglei; Sicard, Taylor; Kucharska, Iga; Li, Wei et al. (2021). Structural details of monoclonal antibody m971 recognition of the membrane-proximal domain of CD22. Journal of Biological Chemistry 297(2) , 100966. 10.1016/j.jbc.2021.100966. [PDB: 7o4y, 7o52] CMCF-ID Health
Epstein, Linda F.; Chen, Hao; Emkey, Renee; Whittington, Douglas A. (2012). The R1275Q Neuroblastoma Mutant and Certain ATP-competitive Inhibitors Stabilize Alternative Activation Loop Conformations of Anaplastic Lymphoma Kinase. Journal of Biological Chemistry 287(44) , 37447-37457. 10.1074/jbc.m112.391425. [PDB: 4fnz] CMCF-ID Health
Elliott, J.Michael; Ultsch, Mark; Lee, Joshua; Tong, Raymond; Takeda, Kentaro et al. (2014). Antiparallel Conformation of Knob and Hole Aglycosylated Half-Antibody Homodimers Is Mediated by a CH2–CH3 Hydrophobic Interaction. Journal of Molecular Biology 426(9) , 1947-1957. 10.1016/j.jmb.2014.02.015. [PDB: 4nqt] CMCF-ID Health
El-Halfawy, Omar M.; Klett, Javier; Ingram, Rebecca J.; Loutet, Slade A.; Murphy, Michael E. P. et al. (2017). Antibiotic Capture by Bacterial Lipocalins Uncovers an Extracellular Mechanism of Intrinsic Antibiotic Resistance. mBio 8(2) , e00225-17. 10.1128/mbio.00225-17. [PDB: 5ixg, 5ixh] CMCF-ID Health