| Aguilar, Eric N.; Sagar, Satish; Murray, Brandy R.; Rajesh, Christabelle; Lei, Eric K. et al. (2024). Structural Basis for Multivalent MUC16 Recognition and Robust Anti-Pancreatic Cancer Activity of Humanized Antibody AR9.6. Molecular Cancer Therapeutics 23(6) , 836-853. 10.1158/1535-7163.mct-23-0868. [PDB: 8gkk, 8gkl] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Bar Ziv, T.; Zhang, D.; Tomlinson, A.C.A.; Knox, J.E.; Yano, J.K. et al. (2024). Tricomplex of RMC-7977, KRAS G12R, and CypA. Protein Data Bank: 8tbh. |
CMCF-ID |
PDB Deposition |
Health |
| Bissegger, Lukas; Constantin, Theodora A.; Keles, Erhan; Raguž, Luka; Barlow-Busch, Isobel et al. (2024). Rapid, potent, and persistent covalent chemical probes to deconvolute PI3Kα signaling. Chemical Science . 10.1039/d4sc05459h. [PDB: 8twy] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Brooks, C.L.; Aguilar, E.N. (2024). Crystal Structure of the Humanized MUC16 Specific Antibody huAR9.6. Protein Data Bank: 8gkl. |
CMCF-ID |
PDB Deposition |
Health |
| Brooks, C.L.; Murray, B. (2024). Crystal Structure of the Humanized MUC16 Specific Antibody huAR9.6. Protein Data Bank: 8gkk. |
CMCF-ID |
PDB Deposition |
Health |
| Chen, A.; Tomlinson, A.C.A.; Knox, J.E.; Yano, J.K. (2024). Tricomplex of RMC-7977, HRAS WT, and CypA. Protein Data Bank: 8tbg. |
CMCF-ID |
PDB Deposition |
Health |
| Critton, D.A. (2024). Crystal structure of monkey TLR7 ectodomain with compound 14. Protein Data Bank: 8s9h. |
CMCF-ID |
PDB Deposition |
Health |
| Daniel-Ivad, Phillip (2024). Crystallographic and biochemical characterization of key steps in reductasporine and capuramycin biosynthesis. Supervisor: Ryan, Katherine S.. BC, Canada: University of British Columbia. http://hdl.handle.net/2429/87410. |
CMCF |
Doctoral Thesis |
Health |
| Daniel-Ivad, Phillip; Ryan, Katherine S. (2024). An imine reductase that captures reactive intermediates in the biosynthesis of the indolocarbazole reductasporine. Journal of Biological Chemistry , 105642. 10.1016/j.jbc.2024.105642. |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Daniel-Ivad, Phillip; Ryan, Katherine S. (2024). Structure of methyltransferase RedM that forms the dimethylpyrrolinium of the bisindole reductasporine. Journal of Biological Chemistry 300(1) , 105520. 10.1016/j.jbc.2023.105520. |
CMCF |
Peer-Reviewed Article |
Health |
| Dementiev, A.A.; Michino, M.; Vendome, J.; Ginn, J.; Bryk, R. et al. (2024). Co-crystal structure of optimized analog TDI-13537 provided new insights into the potency determinants of the sulfonamide inhibitor series. Protein Data Bank: 8u0q. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Dhindwal, P.; Ruzzini, A. (2024). Bile salt hydrolase from Arthrobacter citreus with covalent inhibitor AAA-10 bound. Protein Data Bank: 8vsy. |
CMCF-ID |
PDB Deposition |
Health |
| Folger, Ines B.; Frota, Natália F.; Pistofidis, Angelos; Niquille, David L.; Hansen, Douglas A. et al. (2024). High-throughput reprogramming of an NRPS condensation domain. Nature Chemical Biology . 10.1038/s41589-023-01532-x. [PDB: 8f7f] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Fraser, B.J.; Dong, A.; Ilyassov, O.; Kenney, T.; Li, Y.Y. et al. (2024). Human TMPRSS11D complexed with a disulfide-linked autoinhibitory DDDDK peptide. Protein Data Bank: 8vis. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Gunn, R.J.; Lawson, J.D. (2024). PI3Ka H1047R co-crystal structure with inhibitor in cryptic pocket near H1047R (compound 4).. Protein Data Bank: 8v8h. |
CMCF-ID |
PDB Deposition |
Health |