Publication Beamlines Strategic Pillar
Toure, Momar; Johnson, Theresa; Li, Bin; Schmidt, Ralf; Ma, Hong et al. (2023). Discovery of quinazoline HPK1 inhibitors with high cellular potency. Bioorganic and Medicinal Chemistry 92, 117423. 10.1016/j.bmc.2023.117423. [PDB: 8cij] CMCF-BM Health
Hallett, Robin M.; Bonfill-Teixidor, Ester; Iurlaro, Raffaella; Arias, Alexandra; Raman, Swetha et al. (2022). Therapeutic Targeting of LIF Overcomes Macrophage-mediated Immunosuppression of the Local Tumor Microenvironment. Clinical Cancer Research 29(4) , 791-804. 10.1158/1078-0432.ccr-21-1888. CMCF-ID Health
Richardson-Sanchez, Tomas; Chan, Anson C. K.; Sabatino, Brendil; Lin, Helen; Gaynor, Erin C. et al. (2023). Dissecting components of theCampylobacter jejuni fetMP-fetABCDEFgene cluster in iron scavenging. Tribology Letters . 10.1101/2023.07.05.547857. [PDB: 8t4c] CMCF-ID Health
Chen, Meixia; Wang, Zhuowen; Li, Weiguo; Chen, Yichang; Xiao, Qin et al. (2023). Crystal structure of Tudor domain of TDRD3 in complex with a small molecule antagonist. Biochimica et Biophysica Acta - Gene Regulatory Mechanisms 1866(3) , 194962. 10.1016/j.bbagrm.2023.194962. [PDB: 8jtn] CMCF-ID Health
McGregor, Alexandra K.; Chan, Anson C.K.; Schroeder, Megan D.; Do, Long T.M.; Saini, Gurpreet et al. (2023). A new member of the flavodoxin superfamily from Fusobacterium nucleatum that functions in heme trafficking and reduction of anaerobilin. Journal of Biological Chemistry 299(7) , 104902. 10.1016/j.jbc.2023.104902. [PDB: 8g64] CMCF-BM Health
Duvall, Jeremy R.; Thomas, Joshua D.; Bukhalid, Raghida A.; Catcott, Kalli C.; Bentley, Keith W. et al. (2023). Discovery and Optimization of a STING Agonist Platform for Application in Antibody Drug Conjugates. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.3c00907. [PDB: 8sth] CMCF-ID Health
McLeod, Matthew J.; Holyoak, Todd (2023). Biochemical, structural, and kinetic characterization of PPi‐dependent phosphoenolpyruvate carboxykinase from Propionibacterium freudenreichii. Proteins: Structure. Function and Bioinformatics . 10.1002/prot.26513. [PDB: 8e1u] CMCF-BM Health
Chan, Anson C K; Lin, Helen; Koch, Doreen; Grass, Gregor; Nies, Dietrich H et al. (2020). A copper site is required for iron transport by the periplasmic proteins P19 and FetP. Metallomics 12(10) , 1530-1541. 10.1039/d0mt00130a. CMCF-ID Health
Sharon, Itai; McKay, Geoffrey A.; Nguyen, Dao; Schmeing, T. Martin (2023). Discovery of cyanophycin dipeptide hydrolase enzymes suggests widespread utility of the natural biopolymer cyanophycin. Proceedings of the National Academy of Sciences of the United States of America 120(8) . 10.1073/pnas.2216547120. CMCF-BM Health
McLeod, Matthew J.; Tran, Norman; McCluskey, Gregory D.; Gillis, Tom D.; Bearne, Stephen L. et al. (2023). A metal‐dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine‐5′‐triphosphate. Protein Science 32(6) . 10.1002/pro.4648. [PDB: 8fv6, 8fv7, 8fv8, 8fv9, 8fva, 8fvb] CMCF-BM Health
Gui, Wenjun; Hang, Yumo; Cheng, Wang; Gao, Minqi; Wu, Jiaquan et al. (2023). Structural basis of CDK3 activation by cyclin E1 and inhibition by dinaciclib. Biochemical and Biophysical Research Communications 662, 126-134. 10.1016/j.bbrc.2023.04.026. CMCF-BM, CMCF-ID Health
Mathieu, Sophie; Touvrey, Mélanie; Poulet, Laurent; Drouillard, Sophie; Ulaganathan, Thirumalai Selvi et al. (2023). The porphyran degradation system of the human gut microbiota is complete, phylogenetically diverse and geographically structured across Asian populations. Computerized Medical Imaging and Graphics . 10.1101/2023.03.30.534863. [PDB: 8ep4, 8ew1] CMCF-ID Health
Patel, Ankoor; McBride, Jessica A.M.; Mark, Brian L. (2021). The endopeptidase of the maize-affecting Marafivirus type member maize rayado fino virus doubles as a deubiquitinase. Journal of Biological Chemistry 297(2) , 100957. 10.1016/j.jbc.2021.100957. CMCF Health
van Vliet, Vera J. E.; Huynh, Nhan; Palà, Judith; Patel, Ankoor; Singer, Alex et al. (2022). Ubiquitin variants potently inhibit SARS-CoV-2 PLpro and viral replication via a novel site distal to the protease active site. PLoS Pathogens 18(12) , e1011065. 10.1371/journal.ppat.1011065. CMCF Health
Chen, Sizhu Amelia; Arutyunova, Elena; Lu, Jimmy; Khan, Muhammad Bashir; Rut, Wioletta et al. (2023). SARS-CoV-2 Mpro Protease Variants of Concern Display Altered Viral Substrate and Cell Host Target Galectin-8 Processing but Retain Sensitivity toward Antivirals. ACS Central Science 9(4) , 696-708. 10.1021/acscentsci.3c00054. [PDB: 8djj, 8dk8, 8dkz] CMCF-BM Health