Publication Beamlines Strategic Pillar
Myers, Cullen L.; Li, Franco K.K.; Koo, Byoung-Mo; El-Halfawy, Omar M.; French, Shawn et al. (2016). Identification of Two Phosphate Starvation-induced Wall Teichoic Acid Hydrolases Provides First Insights into the Degradative Pathway of a Key Bacterial Cell Wall Component. Journal of Biological Chemistry 291(50) , 26066-26082. 10.1074/jbc.m116.760447. [PDB: 5t91, 5t9b, 5t9c] CMCF-BM, CMCF-ID Health
McGurn, Leah D.; Moazami-Goudarzi, Maryam; White, Sean A.; Suwal, Tannu; Brar, Beant et al. (2016). The structure, kinetics and interactions of the β-carboxysomal β-carbonic anhydrase, CcaA. Biochemical Journal 473(24) , 4559-4572. 10.1042/bcj20160773. [PDB: 5swc] CMCF-ID Health
Parker, Michelle L.; Houston, Simon; Pětrošová, Helena; Lithgow, Karen V.; Hof, Rebecca et al. (2016). The Structure of Treponema pallidum Tp0751 (Pallilysin) Reveals a Non-canonical Lipocalin Fold That Mediates Adhesion to Extracellular Matrix Components and Interactions with Host Cells. PLoS Pathogens 12(9) , e1005919. 10.1371/journal.ppat.1005919. [PDB: 5jk2] CMCF-ID Health
Reimer, Janice M.; Aloise, Martin N.; Powell, Harold R.; Schmeing, T. Martin (2016). Manipulation of an existing crystal form unexpectedly results in interwoven packing networks with pseudo-translational symmetry. Acta Crystallographica Section D: Structural Biology 72(10) , 1130-1136. 10.1107/s2059798316013504. [PDB: 5jnf] CMCF-ID Health
Zhou, Yan-Feng; Metcalf, Matthew C.; Garman, Scott C.; Edmunds, Tim; Qiu, Huawei et al. (2016). Human acid sphingomyelinase structures provide insight to molecular basis of Niemann–Pick disease. Nature Communications 7(1) . 10.1038/ncomms13082. [PDB: 5i8r] CMCF-ID Health
Noach, Ilit; Ficko-Blean, Elizabeth; Pluvinage, Benjamin; Stuart, Christopher; Jenkins, Meredith L. et al. (2017). Recognition of protein-linked glycans as a determinant of peptidase activity. Proceedings of the National Academy of Sciences of the United States of America 114(5) , E679-E688. 10.1073/pnas.1615141114. [PDB: 5kd5, 5kd8, 5kdn, 5kdu, 5kdv, 5kdw, 5kdx] CMCF-BM, CMCF-ID Health
Sobhanifar, Solmaz; Worrall, Liam J.; King, Dustin T.; Wasney, Gregory A.; Baumann, Lars et al. (2016). Structure and Mechanism of Staphylococcus aureus TarS, the Wall Teichoic Acid β-glycosyltransferase Involved in Methicillin Resistance. PLoS Pathogens 12(12) , e1006067. 10.1371/journal.ppat.1006067. [PDB: 5tzi, 5tzj, 5u02] CMCF-BM, CMCF-ID Health
Almawi, Ahmad W.; Matthews, Lindsay A.; Larasati,; Myrox, Polina; Boulton, Stephen et al. (2016). ‘AND’ logic gates at work: Crystal structure of Rad53 bound to Dbf4 and Cdc7. Scientific Reports 6(1) . 10.1038/srep34237. [PDB: 5t2s] CMCF-BM Health
Ulaganathan, ThirumalaiSelvi; Shi, Rong; Yao, Deqiang; Gu, Ruo-Xu; Garron, Marie-Line et al. (2016). Conformational flexibility of PL12 family heparinases: structure and substrate specificity of heparinase III fromBacteroides thetaiotaomicron(BT4657). Glycobiology 27(2) , 176-187. 10.1093/glycob/cww096. [PDB: 5jmd, 5jmf] CMCF-ID Health
Haji-Ghassemi, Omid; Gilbert, Michel; Spence, Jenifer; Schur, Melissa J.; Parker, Matthew J. et al. (2016). Molecular Basis for Recognition of the Cancer Glycobiomarker, LacdiNAc (GalNAc[β1→4]GlcNAc), by Wisteria floribunda Agglutinin. Journal of Biological Chemistry 291(46) , 24085-24095. 10.1074/jbc.m116.750463. [PDB: 5kxb, 5kxc, 5kxd, 5kxe] CMCF-ID Health
Torres, Miguel A.; Hoffarth, Elesha; Eugenio, Luiz; Savtchouk, Julia; Chen, Xue et al. (2016). Structural and Functional Studies of Pavine N-Methyltransferase from Thalictrum flavum Reveal Novel Insights into Substrate Recognition and Catalytic Mechanism. Journal of Biological Chemistry 291(45) , 23403-23415. 10.1074/jbc.m116.747261. [PDB: 5kn4, 5kpc, 5kpg] CMCF-BM Health
Wu, Yong-Jin; Guernon, Jason; Shi, Jianliang; Marcin, Lawrence; Higgins, Mendi et al. (2016). Discovery of S3-Truncated, C-6 Heteroaryl Substituted Aminothiazine β-Site APP Cleaving Enzyme-1 (BACE1) Inhibitors. Journal of Medicinal Chemistry 59(18) , 8593-8600. 10.1021/acs.jmedchem.6b01012. [PDB: 5kr8] CMCF-ID Health
Lee, Samuel K.; Shanmughapriya, Santhanam; Mok, Mac C.Y.; Dong, Zhiwei; Tomar, Dhanendra et al. (2016). Structural Insights into Mitochondrial Calcium Uniporter Regulation by Divalent Cations. Cell Chemical Biology 23(9) , 1157-1169. 10.1016/j.chembiol.2016.07.012. [PDB: 5kue, 5kug, 5kui, 5kuj] CMCF-ID Health
Sahtout, Naheda; Kuttiyatveetil, Jijin R. A.; Fodje, Michel; Sanders, David A. R. (2016). Putative thioredoxin Trx1 fromThermosipho africanusstrain TCF52B: expression, purification and structural determination using S-SAD. Acta Crystallographica Section F:Structural Biology Communications 72(6) , 443-447. 10.1107/s2053230x16007214. CMCF-BM Health
Hughes, Scott J.; Barnard, Leanne; Mottaghi, Katayoun; Tempel, Wolfram; Antoshchenko, Tetyana et al. (2016). Discovery of Potent Pantothenamide Inhibitors of Staphylococcus aureus Pantothenate Kinase through a Minimal SAR Study: Inhibition Is Due to Trapping of the Product. ACS Infectious Diseases 2(9) , 627-641. 10.1021/acsinfecdis.6b00090. [PDB: 5jic] CMCF-ID Health