| Sachdev Sidhu; Linda Beatty; Andreas Ernst (2012). Specific active site inhibitors of enzymes or substrate binding partners and methods of producing same. Patent Number: CA2807774A1. |
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| Little, Dustin J.; Milek, Sonja; Bamford, Natalie C.; Ganguly, Tridib; DiFrancesco, Benjamin R. et al. (2015). The Protein BpsB Is a Poly-β-1,6-N-acetyl-d-glucosamine Deacetylase Required for Biofilm Formation in Bordetella bronchiseptica. Journal of Biological Chemistry 290(37) , 22827-22840. 10.1074/jbc.m115.672469. [PDB: 5bu6] |
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| Taylor, Alexander M.; Vaswani, Rishi G.; Gehling, Victor S.; Hewitt, Michael C.; Leblanc, Yves et al. (2015). Discovery of Benzotriazolo[4,3-d][1,4]diazepines as Orally Active Inhibitors of BET Bromodomains. ACS Medicinal Chemistry Letters 7(2) , 145-150. 10.1021/ml500411h. [PDB: 4z1s] |
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| Grebien, Florian; Vedadi, Masoud; Getlik, Matthäus; Giambruno, Roberto; Grover, Amit et al. (2015). Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia. Nature Chemical Biology 11(8) , 571-578. 10.1038/nchembio.1859. [PDB: 4ql1] |
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| Ndubaku, Chudi O.; Crawford, Terry D.; Chen, Huifen; Boggs, Jason W.; Drobnick, Joy et al. (2015). Structure-Based Design of GNE-495, a Potent and Selective MAP4K4 Inhibitor with Efficacy in Retinal Angiogenesis. ACS Medicinal Chemistry Letters 6(8) , 913-918. 10.1021/acsmedchemlett.5b00174. |
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| Haji-Ghassemi, Omid; Müller-Loennies, Sven; Rodriguez, Teresa; Brade, Lore; Kosma, Paul et al. (2015). Structural Basis for Antibody Recognition of Lipid A. Journal of Biological Chemistry 290(32) , 19629-19640. 10.1074/jbc.m115.657874. [PDB: 4odt, 4odu, 4odv, 4odw, 4z8f, 4z95] |
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| Haji-Ghassemi, O.; Evans, S.V. (2015). Fab structure of antibody S1-15 in complex with ssDNA DNA, 5'-p5(dT)p-3'. Protein Data Bank: 4z8f. |
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Health |
| Haji-Ghassemi, O.; Evans, S.V. (2015). Unliganded Fab structure of lipid A-specific antibody S1-15. Protein Data Bank: 4odu. |
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PDB Deposition |
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| Haji-Ghassemi, O.; Evans, S.V. (2015). Fab Structure of lipid A-specific antibody S1-15 in complex with lipid A carbohydrate backbone. Protein Data Bank: 4odt. |
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PDB Deposition |
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| Haji-Ghassemi, O.; Evans, S.V. (2015). Unliganded Fab structure of lipid A-specific antibody A6. Protein Data Bank: 4odw. |
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PDB Deposition |
Health |
| Haji-Ghassemi, O.; Evans, S.V. (2015). Fab Structure of lipid A-specific antibody A6 in complex with lipid A carbohydrate backbone. Protein Data Bank: 4odv. |
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PDB Deposition |
Health |
| Haji-Ghassemi, O.; Evans, S.V. (2015). Fab structure of antibody S1-15 in complex with ssDNA DNA, 5'-5(dT)-p-3'. Protein Data Bank: 4z95. |
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PDB Deposition |
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| Pfoh, R.; Lacdao, I.K.L.; Saridakis, V. (2015). Crystal structure of USP7 ubiquitin-like domains in extended conformation. Protein Data Bank: 4wpi. |
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| Pfoh, Roland; Lacdao, Ira Kay; Georges, Anna A.; Capar, Adam; Zheng, Hong et al. (2015). Crystal Structure of USP7 Ubiquitin-like Domains with an ICP0 Peptide Reveals a Novel Mechanism Used by Viral and Cellular Proteins to Target USP7. PLoS Pathogens 11(6) , e1004950. 10.1371/journal.ppat.1004950. [PDB: 4wpi] |
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| Singh, Sheo B.; Kaelin, David E.; Wu, Jin; Miesel, Lynn; Tan, Christopher M. et al. (2015). Tricyclic 1,5-naphthyridinone oxabicyclooctane-linked novel bacterial topoisomerase inhibitors as broad-spectrum antibacterial agents-SAR of left-hand-side moiety (Part-2). Bioorganic and Medicinal Chemistry Letters 25(9) , 1831-1835. 10.1016/j.bmcl.2015.03.044. [PDB: 5bs3] |
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