| Abbas, Yazan M.; Laudenbach, Beatrice Theres; Martínez-Montero, Saúl; Cencic, Regina; Habjan, Matthias et al. (2017). Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2′-O methylations. Proceedings of the National Academy of Sciences of the United States of America 114(11) , E2106-E2115. 10.1073/pnas.1612444114. [PDB: 5udi, 5udj, 5udk, 5udl] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Muckelbauer, J.K. (2017). Crystal structure of Bruton agammabulinemia tyrosine kinase complexed with BMS-986142 aka (2s)-6-fluoro-5-[3-(8-fluoro-1-methyl-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl)-2-methylphenyl]-2-(2-hydroxypropan-2-yl)-2,3,4,9-tetrahydro-1h-carbazole-8-carboxamide. Protein Data Bank: 5t18. |
CMCF-ID |
PDB Deposition |
Health |
| Watterson, Scott H.; De Lucca, George V.; Shi, Qing; Langevine, Charles M.; Liu, Qingjie et al. (2016). Discovery of 6-Fluoro-5-(R)-(3-(S)-(8-fluoro-1-methyl-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)-2-methylphenyl)-2-(S)-(2-hydroxypropan-2-yl)-2,3,4,9-tetrahydro-1H-carbazole-8-carboxamide (BMS-986142): A Reversible Inhibitor of Bruton’s Tyrosine Kinase (BTK) Conformationally Constrained by Two Locked Atropisomers. Journal of Medicinal Chemistry 59(19) , 9173-9200. 10.1021/acs.jmedchem.6b01088. [PDB: 5t18] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Abbas, Y.M.; Martinez-Montero, S.; Damha, M.J.; Nagar, B. (2017). IFIT1 N216A monomeric mutant (L457E/L464E) with m7Gppp-AAAA (anti conformation of cap). Protein Data Bank: 5udl. |
CMCF-ID |
PDB Deposition |
Health |
| Abbas, Y.M.; Martinez-Montero, S.; Damha, M.J.; Nagar, B. (2017). IFIT1 monomeric mutant (L457E/L464E) with PPP-AAAA. Protein Data Bank: 5udk. |
CMCF-ID |
PDB Deposition |
Health |
| Abbas, Y.M.; Martinez-Montero, S.; Damha, M.J.; Nagar, B. (2017). IFIT1 monomeric mutant (L457E/L464E) with Gppp-AAAA. Protein Data Bank: 5udj. |
CMCF-ID |
PDB Deposition |
Health |
| Abbas, Y.M.; Martinez-Montero, S.; Damha, M.J.; Nagar, B. (2017). IFIT1 monomeric mutant (L457E/L464E) with m7Gppp-AAAA (syn and anti conformations of cap). Protein Data Bank: 5udi. |
CMCF-ID |
PDB Deposition |
Health |
| Arya, T.; Sharifahmadian, M.; Sygusch, J.; Baron, B. (2017). Conformational changes during monomer-to-dimer transition of Brucella suis VirB8. Protein Data Bank: 5jbs. |
CMCF-ID |
PDB Deposition |
Health |
| Seattle Structural Genomics Center for Infectious Disease (SSGCID) (2017). Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to follow on fragment EBSI-4721 1-(4-fluorophenyl)-1H-imidazole. Protein Data Bank: 5ifd. |
CMCF-ID |
PDB Deposition |
Health |
| Seattle Structural Genomics Center for Infectious Disease (SSGCID) (2017). Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to fragment hit EBSI-2643 5-[(4-chlorophenyl)methyl]-1,3,4-oxadiazol-2-amine. Protein Data Bank: 5if8. |
CMCF-ID |
PDB Deposition |
Health |
| Seattle Structural Genomics Center for Infectious Disease (SSGCID) (2017). Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to follow on fragment EBSI-4720 1-(4-bromophenyl)-1H-imidazole. Protein Data Bank: 5ifc. |
CMCF-ID |
PDB Deposition |
Health |
| Grochulski, Pawel; Fodje, Michel; Labiuk, Shaun; Wysokinski, Tomasz W.; Belev, George et al. (2017). Review of Canadian Light Source facilities for biological applications. Nuclear Instruments and Methods in Physics Research. Section B: Beam Interactions with Materials and Atoms 411, 17-21. 10.1016/j.nimb.2017.01.065. |
BIOXAS, BMIT-BM, BMIT-ID, CMCF-BM, CMCF-ID, MID-IR |
Peer-Reviewed Article |
Health |
| Richter, Jeremy M.; Cheney, Daniel L.; Bates, J. Alex; Wei, Anzhi; Luettgen, Joseph M. et al. (2016). Design and Synthesis of Novel Meta-Linked Phenylglycine Macrocyclic FVIIa Inhibitors. ACS Medicinal Chemistry Letters 8(1) , 67-72. 10.1021/acsmedchemlett.6b00375. [PDB: 5tqe] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Park, J.; Zielinski, M.; Tsantrizos, Y.S.; Berghuis, A.M. (2017). Crystal structure of human FPPS with allosterically bound FPP. Protein Data Bank: 5ja0. |
CMCF-ID |
PDB Deposition |
Health |
| Park, Jaeok; Zielinski, Michal; Magder, Alexandr; Tsantrizos, Youla S.; Berghuis, Albert M. et al. (2017). Human farnesyl pyrophosphate synthase is allosterically inhibited by its own product. Nature Communications 8(1) . 10.1038/ncomms14132. [PDB: 5ja0] |
CMCF-ID |
Peer-Reviewed Article |
Health |