Publication Beamlines Strategic Pillar
Merchant, Rohan R.; Chernyak, Natalia; Lopez, Jovan A.; Sharp, Phillip P.; Mandal, Mihir et al. (2026). N -Alkyl and N -Aryl Aminopyrazole Spirocarbamates: A Two-Pronged Lead Optimization Strategy to Identify Orally Bioavailable Plasma Kallikrein Inhibitors. ACS Medicinal Chemistry Letters 17(3) , 744-749. 10.1021/acsmedchemlett.6c00066. [PDB: 10qs] CMCF-BM Agriculture
Mendoza, M.N.; Jian, M.; Toride King, M.; Brooks, C.L. (2020). VHH R303 C33A/C102A in complex withthe LRR domain of InlB. Protein Data Bank: 6u14. CMCF-ID Health
Mendoza, M.N.; Jian, M.; Toride King, M.; Brooks, C.L. (2020). VHH R303 C33A/C102A in complex withthe LRR domain of InlB. Protein Data Bank: 6u12. CMCF-ID Health
Mendoza, Matthew N.; Jian, Mike; King, Moeko T.; Brooks, Cory L. (2020). Role of a noncanonical disulfide bond in the stability, affinity, and flexibility of a VHH specific for the Listeria virulence factor InlB. Protein Science 29(4) , 1004-1017. 10.1002/pro.3831. [PDB: 6u12, 6u14] CMCF-ID Health
Mendez, Alex; Bolling, Cydni; Taylor, Shane; Makumire, Stanley; Staker, Bart et al. (2025). Structure of Plasmodium vivax N-myristoyltransferase with inhibitor IMP-1088: exploring an NMT inhibitor for antimalarial therapy. Acta Crystallographica Section F:Structural Biology Communications 81(1) , 1-10. 10.1107/s2053230x24011348. [PDB: 5v0w] CMCF-ID Health
Mellouk, A.; Calmettes, C. (2026). Crystal structure of Class-3 OPX WzaB from Myxococcus xanthus. Protein Data Bank: 9n9a. CMCF-BM Agriculture
Mellouk, Abdelkader; Ngo, Kenny; Kezzo, Ahmad A.; Martini, Cyrielle; França, Tanos C. C. et al. (2026). Mechanism of trans-envelope bacterial polysaccharide secretion in Class-3 outer-membrane polysaccharide export (OPX) protein systems. Nature Communications . 10.1038/s41467-025-67321-3. [PDB: 9n9a] CMCF-BM Health
Mellor, Paul; Marshall, Jeremy D. S.; Ruan, Xuan; Whitecross, Dielle E.; Ross, Rebecca L. et al. (2018). Patient-derived mutations within the N-terminal domains of p85α impact PTEN or Rab5 binding and regulation. Scientific Reports 8(1) . 10.1038/s41598-018-25487-5. [PDB: 6d81, 6d82, 6d85, 6d86, 6d87] CMCF-BM, CMCF-ID Health
Meier, M.; Nikodemus, D.; Reuten, R.; Patel, T.R.; Orriss, G. et al. (2015). X-ray Crystal Structure of Mouse Netrin-1. Protein Data Bank: 4ove. CMCF-BM Health
Meier, Markus; Gupta, Monika; Akgül, Serife; McDougall, Matthew; Imhof, Thomas et al. (2023). The dynamic nature of netrin-1 and the structural basis for glycosaminoglycan fragment-induced filament formation. Nature Communications 14(1) . 10.1038/s41467-023-36692-w. CMCF Health
McTigue, M.; Deng, Y.-L.; Liu, W.; Brooun, A.; Stewart, A. et al. (2016). Structure of C1156Y Mutant Human Anaplastic Lymphoma Kinase in Complex with PF-06463922 ((10R)-7-amino-12-fluoro-2,10,16-trimethyl- 15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo(4,3-h)(2,5,11) benzoxadiazacyclotetradecine-3-carbonitrile).. Protein Data Bank: 5a9u. CMCF-ID Health
McTigue, M.; Deng, Y.; Liu, W.; Brooun, A.; Stewart, A. et al. (2016). Structure of C1156Y Mutant Human Anaplastic Lymphoma Kinase in Complex with Crizotinib. Protein Data Bank: 5aac. CMCF-ID Health
McTigue, M.; Deng, Y.; Liu, W.; Brooun, A.; Stewart, A. et al. (2013). Structure of Human ROS1 Kinase Domain in Complex with Crizotinib. Protein Data Bank: 3zbf. CMCF-ID Health
McTigue, M.A.; Deng, Y.L.; Liu, W.; Brooun, A.; Stewart, A.E. et al. (2014). Structure of the Human Anaplastic Lymphoma Kinase in Complex with the inhibitor (5R)-8-amino-3-fluoro-5,19-dimethyl-20-oxo-5,18,19,20- tetrahydro-7,11-(azeno)pyrido(2',1':2,3)imidazo(4,5-h)(2,5,11) benzoxadiazacyclotetradecine-14-carbonitrile. Protein Data Bank: 4ctb. CMCF-ID Health
McPhail, Jacob A.; Ottosen, Erik H.; Jenkins, Meredith L.; Burke, John E. (2017). The Molecular Basis of Aichi Virus 3A Protein Activation of Phosphatidylinositol 4 Kinase IIIβ, PI4KB, through ACBD3. Structure 25(1) , 121-131. 10.1016/j.str.2016.11.016. [PDB: 5tdq] CMCF-ID Health