Publication Beamlines Strategic Pillar
Sychantha, David; Little, Dustin J; Chapman, Robert N; Boons, Geert-Jan; Robinson, Howard et al. (2017). PatB1 is an O-acetyltransferase that decorates secondary cell wall polysaccharides. Nature Chemical Biology 14(1) , 79-85. 10.1038/nchembio.2509. [PDB: 5v8e] CMCF-BM Health
Tarry, Michael J.; Haque, Asfarul S.; Bui, Khanh Huy; Schmeing, T. Martin (2017). X-Ray Crystallography and Electron Microscopy of Cross- and Multi-Module Nonribosomal Peptide Synthetase Proteins Reveal a Flexible Architecture. Structure 25(5) , 783-793.e4. 10.1016/j.str.2017.03.014. [PDB: 5u89] CMCF-ID Health
Triller, Gianna; Scally, Stephen W.; Costa, Giulia; Pissarev, Maria; Kreschel, Cornelia et al. (2017). Natural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies. Immunity 47(6) , 1197-1209.e10. 10.1016/j.immuni.2017.11.007. [PDB: 5bk0, 5bk3, 5bk5, 6azm, 6azx] CMCF-ID Health
Ulaganathan, ThirumalaiSelvi; Boniecki, Michal T.; Foran, Elizabeth; Buravenkov, Vitaliy; Mizrachi, Naama et al. (2017). New Ulvan-Degrading Polysaccharide Lyase Family: Structure and Catalytic Mechanism Suggests Convergent Evolution of Active Site Architecture. ACS Chemical Biology 12(5) , 1269-1280. 10.1021/acschembio.7b00126. [PDB: 5uam, 5uas] CMCF-BM Health
Vadlamani, Grishma; Stubbs, Keith A.; Désiré, Jérôme; Blériot, Yves; Vocadlo, David J. et al. (2017). Conformational flexibility of the glycosidase NagZ allows it to bind structurally diverse inhibitors to suppress β-lactam antibiotic resistance. Protein Science 26(6) , 1161-1170. 10.1002/pro.3166. [PDB: 5utr] CMCF-BM Health
Wahba, Haytham M.; Stevenson, Michael J.; Mansour, Ahmed; Sygusch, Jurgen; Wilcox, Dean E. et al. (2017). Structural and Biochemical Characterization of Organotin and Organolead Compounds Binding to the Organomercurial Lyase MerB Provide New Insights into Its Mechanism of Carbon–Metal Bond Cleavage. Journal of the American Chemical Society 139(2) , 910-921. 10.1021/jacs.6b11327. [PDB: 5u79, 5u7b, 5u7c, 5u82, 5u83] CMCF-ID Health
Wilsbacher, Julie L.; Cheng, Min; Cheng, Dong; Trammell, Samuel A.J.; Shi, Yan et al. (2017). Discovery and Characterization of Novel Nonsubstrate and Substrate NAMPT Inhibitors. Molecular Cancer Therapeutics 16(7) , 1236-1245. 10.1158/1535-7163.mct-16-0819. [PDB: 5u2m] CMCF-ID Health
Wong, Alan H. M.; Tomlinson, Aidan C. A.; Zhou, Dongxia; Satkunarajah, Malathy; Chen, Kevin et al. (2017). Receptor-binding loops in alphacoronavirus adaptation and evolution. Nature Communications 8(1) . 10.1038/s41467-017-01706-x. [PDB: 6atk] CMCF-ID Health
Wong King Yuen, Siobhan M.; Campiglio, Marta; Tung, Ching-Chieh; Flucher, Bernhard E.; Van Petegem, Filip et al. (2017). Structural insights into binding of STAC proteins to voltage-gated calcium channels. Proceedings of the National Academy of Sciences of the United States of America 114(45) , 201708852. 10.1073/pnas.1708852114. [PDB: 6b29] CMCF-ID Health
Wong, Norman E.; Ramaswamy, Padmini; Lee, Andrew S.; Gelfand, Benjamin S.; Bladek, Kamila J. et al. (2017). Tuning Intrinsic and Extrinsic Proton Conduction in Metal–Organic Frameworks by the Lanthanide Contraction. Journal of the American Chemical Society 139(41) , 14676-14683. 10.1021/jacs.7b07987. CMCF-BM Materials
Xiong, Yumei; Walker, Kenneth; Min, Xiaoshan; Hale, Clarence; Tran, Thanhvien et al. (2017). Long-acting MIC-1/GDF15 molecules to treat obesity: Evidence from mice to monkeys. Science Translational Medicine 9(412) , eaan8732. 10.1126/scitranslmed.aan8732. [PDB: 5vt2] CMCF-ID Health
Yazdi, Aliakbar Khalili; Vezina, Grant C.; Shilton, Brian H. (2017). An alternate mode of oligomerization for E. coli SecA. Scientific Reports 7(1) . 10.1038/s41598-017-11648-5. [PDB: 5k9t] CMCF-ID Health
Yeung, Kap-Sun; Beno, Brett R.; Parcella, Kyle; Bender, John A.; Grant-Young, Katherine A. et al. (2017). Discovery of a Hepatitis C Virus NS5B Replicase Palm Site Allosteric Inhibitor (BMS-929075) Advanced to Phase 1 Clinical Studies. Journal of Medicinal Chemistry 60(10) , 4369-4385. 10.1021/acs.jmedchem.7b00328. [PDB: 5pzp] CMCF-ID Health
Zhang, Heng; Liu, Ke; Izumi, Natsuko; Huang, Haiming; Ding, Deqiang et al. (2017). Structural basis for arginine methylation-independent recognition of PIWIL1 by TDRD2. Proceedings of the National Academy of Sciences of the United States of America 114(47) , 12483-12488. 10.1073/pnas.1711486114. [PDB: 5j39] CMCF-ID Health
Zhang, Wei; Bailey-Elkin, Ben A.; Knaap, Robert C. M.; Khare, Baldeep; Dalebout, Tim J. et al. (2017). Potent and selective inhibition of pathogenic viruses by engineered ubiquitin variants. PLoS Pathogens 13(5) , e1006372. 10.1371/journal.ppat.1006372. [PDB: 5v5g, 5v5h, 5v6a] CMCF-BM, CMCF-ID Health