Publication Beamlines Strategic Pillar
Merchant, R.R.; Chernyak, N.; Lopez, J.A.; Sharp, P.P.; Mandal, M. et al. (2026). N-Alkyl & N-Aryl Aminopyrazole Spirocarbamates: A Two-Pronged Lead Optimization Strategy to Identify Orally Bioavailable Plasma Kallikrein Inhibitors Compound 13 ((3'R)-1'-{5-amino-1-[(2S)-1,1,1-trifluorobutan-2-yl]-1H-pyrazole-4-carbonyl}-6-chloro-5-fluorospiro[[3,1]benzoxazine-4,3'-piperidin]-2(1H)-one). Protein Data Bank: 10qs. CMCF-BM Materials
Lamberink, Jan-Willem; Kassymbek, Aishabibi; Dmitrienko, Anton; Spasyuk, Denis; Gabidullin, Bulat et al. (2026). Germylide-Catalyzed Hydrosilylation and Hydroboration: Insertion/Metathesis versus Non-hydride Mechanisms. Inorganic Chemistry . 10.1021/acs.inorgchem.6c02932. CMCF-BM Materials
Boraston, A.B.; Tingley, J.; Mihalynuk, L.; Abbott, D.W. (2026). Structure of a GH16_17 carrageenase from a metagenomic dataset.. Protein Data Bank: 9efl. CMCF-ID Health
Fong, J.K.; Cordeiro, R.L.; Van Petegem, F.; Brumer, H. (2026). Structure of glyoxal oxidase from Fusarium graminearum at 1.28 Angstroms resolution. Protein Data Bank: 9n3u. CMCF-ID Health
Ivanochko, D.; Semesi, A.; Julien, J.P. (2026). Tandem antigen chimera of Pfs230 and Pfs48/45 bound by potent mAbs. Protein Data Bank: 9n8n. CMCF-ID Health
Palte, R.L.; Eddins, M.; Vara, B.A.; Schneider, S.E. (2026). Crystal structure of TEAD2 with non-covalent aryl ether inhibitor.. Protein Data Bank: 9yk2. CMCF-BM Health
Tran, N.; Holyoak, T. (2026). Crystal structure of the Streptococcus pneumoniae HtrA protease PDZ domain. Protein Data Bank: 9pno. CMCF-BM Health
Yazdani, Shauhin (2026). Biophysical and Structural Characterization of the Metronidazole Resistance Protein NimB from Clostridioides difficile. Supervisor: Holyoak, Todd. Ontario, Canada: University of Waterloo. https://hdl.handle.net/10012/23962. CMCF-BM Health
Aljghami, Mazen E.; Morey, Trevor M.; Mabanglo, Mark F.; Meyrick, Jonathan J.; Thomas, Huw B. et al. (2026). Identification of substrates of the human mitochondrial ClpXP protease and its implications for Perrault syndrome. Nature Communications . 10.1038/s41467-026-77888-0. CMCF-BM Health
Andress, Sam; McLeod, Matthew J.; Holyoak, Todd (2026). The C117D oxidation mimic reveals the monomeric structure of SARS ‐ CoV ‐2 main protease. Protein Science 35(9) . 10.1002/pro.70753. CMCF-ID Health
Carbone, Christine E.; Schönherr, Heike; Zhao, Victor Y.; Pierce, Levi; He, Jing et al. (2026). Cryptic small-molecule binding sites in the ARID1B DNA-binding domain. Proceedings of the National Academy of Sciences of the United States of America 123(33) . 10.1073/pnas.2529603123. CMCF-ID Health
Chatterjee, Som; Poon, Raymond; Satishkumar, Nidhi; Mosimann, Wesley; Hayatnagarkar, Vedangi et al. (2026). Stk1 is required for BlaR1-mediated broad-spectrum β-lactam resistance in epidemic-causing strains of Staphylococcus aureus. Materials & Design . 10.21203/rs.3.rs-8331258/v1. [PDB: 9ymt] CMCF-BM Health
Di Lello, Paola; Wells, Marta M.; Davis, Ben; Daniels, Zoe; Garner, Thomas P. et al. (2026). Targeting PTPN22 at Nonorthosteric Binding Sites─A Fragment Approach. ACS Omega . 10.1021/acsomega.5c11028. [PDB: 9yg0, 9yg1, 9yg3] CMCF-BM Health
Govind, Manitabhai; Allas, Mikel Jason; Huang, Bo-Shun; Lowary, Todd L.; Kimber, Matthew S. et al. (2026). The retaining kdo transferase that synthesizes Escherichia coli K13 capsule is deeply divergent from structurally homologous enzymes. Journal of Biological Chemistry 302(3) , 111162. 10.1016/j.jbc.2026.111162. [PDB: 9yfx] CMCF-ID Health
Haines, Eric; Burke, Michael; Catterall, Rachel; De Jesus, Victor; Hidalgo, Daniel et al. (2026). The MEK–RAF molecular glue IK-595 has potent antitumor activity across RAS/MAPK pathway-altered cancers. Nature Cancer . 10.1038/s43018-025-01081-3. [PDB: 9ecu] CMCF-ID Health