Publication Beamlines Strategic Pillar
Haines, Eric; Burke, Michael; Catterall, Rachel; De Jesus, Victor; Hidalgo, Daniel et al. (2026). The MEK–RAF molecular glue IK-595 has potent antitumor activity across RAS/MAPK pathway-altered cancers. Nature Cancer . 10.1038/s43018-025-01081-3. [PDB: 9ecu] CMCF-ID Health
Govind, Manitabhai; Allas, Mikel Jason; Huang, Bo-Shun; Lowary, Todd L.; Kimber, Matthew S. et al. (2026). The retaining kdo transferase that synthesizes Escherichia coli K13 capsule is deeply divergent from structurally homologous enzymes. Journal of Biological Chemistry 302(3) , 111162. 10.1016/j.jbc.2026.111162. [PDB: 9yfx] CMCF-ID Agriculture
Yang, A. (2026). Crystal structure of the inactive BRAF/MEK1 complex bound to IK-595. Protein Data Bank: 9ecu. CMCF-ID Agriculture
Qiu, Y. (2026). Crystal structure of BCMA in complex with CA10v2 Fab. Protein Data Bank: 9mqo. CMCF-ID Agriculture
kimani, S.; Dong, A.; Li, Y.; Seitova, A.; Mamai, A. et al. (2026). Crystal structure of the human DCAF1 WDR domain in complex with OICR-40102. Protein Data Bank: 9y4q. CMCF-ID Agriculture
Govind, M.; Kimber, M.S. (2026). KrKA retaining Kdo transferase CMP complex. Protein Data Bank: 9yfx. CMCF-ID Agriculture
Ereno-Orbea, J.; Sicard, T.; Julien, J.-P. (2026). Crystal structure of human CD22 Ig domains 1-3 in complex with modified sialoside 17. Protein Data Bank: 9rm3. CMCF-ID Agriculture
Van Schepdael, Matthew; Asakereh, Iman; Colautti, Jake; Gierys, Andrew J.; Sachar, Kartik et al. (2026). Biophysical characterization of Eag chaperones suggests the mechanism of effector transmembrane domain release. Nature Communications . 10.1038/s41467-025-68138-w. [PDB: 9mvg] CMCF-BM Health
Mellouk, Abdelkader; Ngo, Kenny; Kezzo, Ahmad A.; Martini, Cyrielle; França, Tanos C. C. et al. (2026). Mechanism of trans-envelope bacterial polysaccharide secretion in Class-3 outer-membrane polysaccharide export (OPX) protein systems. Nature Communications . 10.1038/s41467-025-67321-3. [PDB: 9n9a] CMCF-BM Health
Di Lello, Paola; Wells, Marta M.; Davis, Ben; Daniels, Zoe; Garner, Thomas P. et al. (2026). Targeting PTPN22 at Nonorthosteric Binding Sites─A Fragment Approach. ACS Omega . 10.1021/acsomega.5c11028. [PDB: 9yg0, 9yg1, 9yg3] CMCF-BM Health
Van Schepdael, M.A.; Prehna, G. (2026). Structure of SciW variant L66A bound to the Rhs1 transmembrane domain. Protein Data Bank: 9mvg. CMCF-BM Agriculture
Sachark, K.; Van Schepdael, M.; Winters, K.L.; Prehna, G. (2026). Crystal structure of VgrS from Salmonella Typhimurium. Protein Data Bank: 9mlp. CMCF-BM Agriculture
Mellouk, A.; Calmettes, C. (2026). Crystal structure of Class-3 OPX WzaB from Myxococcus xanthus. Protein Data Bank: 9n9a. CMCF-BM Agriculture
Di Lello, P.; Wells, M.M. (2026). Targeting PTPN22 at non-orthosteric binding sites - a fragment approach. Protein Data Bank: 9yg3. CMCF-BM Agriculture
Di Lello, P.; Wells, M.M. (2026). Targeting PTPN22 at non-orthosteric binding sites - a fragment approach. Protein Data Bank: 9yg1. CMCF-BM Agriculture