| Merchant, R.R.; Chernyak, N.; Lopez, J.A.; Sharp, P.P.; Mandal, M. et al. (2026). N-Alkyl & N-Aryl Aminopyrazole Spirocarbamates: A Two-Pronged Lead Optimization Strategy to Identify Orally Bioavailable Plasma Kallikrein Inhibitors Compound 13 ((3'R)-1'-{5-amino-1-[(2S)-1,1,1-trifluorobutan-2-yl]-1H-pyrazole-4-carbonyl}-6-chloro-5-fluorospiro[[3,1]benzoxazine-4,3'-piperidin]-2(1H)-one). Protein Data Bank: 10qs. |
CMCF-BM |
PDB Deposition |
Materials |
| Dodda, Leela S.; Campos, Sebastien; Ciccone, David; Carreiro, Samantha; Leit, Silvana et al. (2025). Knowledge and Structure-Based Drug Design of 15-PGDH Inhibitors. Journal of Medicinal Chemistry 68(17) , 18436-18462. 10.1021/acs.jmedchem.5c01231. [PDB: 9pfl] |
CMCF-BM |
Peer-Reviewed Article |
Materials |
| Zhao, Feipeng; Zhang, Shumin; Wang, Shuo; Reid, Joel W.; Xia, Wei et al. (2025). Anion sublattice design enables superionic conductivity in crystalline oxyhalides. Science 390(6769) , 199-204. 10.1126/science.adt9678. |
CMCF-BM, SXRMB |
Peer-Reviewed Article |
Materials |
| Lu, Jimmy (2025). Mechanistic Insights into Protease Function and Inhibition in Infectious Diseases. Supervisor: Lemieux, M. Joanne. Alberta, Canada: University of Alberta. https://doi.org/10.7939/83361. |
CMCF-BM |
Doctoral Thesis |
Health |
| Boraston, A.B.; Tingley, J.; Mihalynuk, L.; Abbott, D.W. (2026). Structure of a GH16_17 carrageenase from a metagenomic dataset.. Protein Data Bank: 9efl. |
CMCF-ID |
PDB Deposition |
Health |
| Chen, A.; Tomlinson, A.C.A.; Bieder, R.; Knox, J.E.; Yano, J.K. et al. (2025). Tri-complex of Daraxonrasib (RMC-6236), KRAS G12C, and CypA. Protein Data Bank: 9bga. |
CMCF-ID |
PDB Deposition |
Health |
| Costanzi, E.; Thomsen, M. (2025). The crystal structure of FAN1 Nuclease bound to 5' phosphorylated p(dG)/3'(dT-dT-dT-dT) double flap DNA. Protein Data Bank: 8s5a. |
CMCF-ID |
PDB Deposition |
Health |
| Ezekiel, S.; Park, J. (2025). Structure of mutant human geranylgeranyl pyrophosphate synthase (Y246D-C247L) in complex with isopentenyl pyrophosphate. Protein Data Bank: 9csl. |
CMCF-ID |
PDB Deposition |
Health |
| Fan, S.; Wei, X.; Lv, R.; Wang, C.; Tang, M. et al. (2025). Crystal structure of serine hydroxymethyltransferase 1. Protein Data Bank: 8xnd. |
CMCF-ID |
PDB Deposition |
Health |
| Fan, S.; Wei, X.; Lv, R.; Wang, C.; Tang, M. et al. (2025). The Crystal Structure of Glucosyltransferase TcdB from Clostridioides difficile. Protein Data Bank: 8y2l. |
CMCF-ID |
PDB Deposition |
Health |
| Fong, J.K.; Cordeiro, R.L.; Van Petegem, F.; Brumer, H. (2026). Structure of glyoxal oxidase from Fusarium graminearum at 1.28 Angstroms resolution. Protein Data Bank: 9n3u. |
CMCF-ID |
PDB Deposition |
Health |
| Fontano, E.; Suto, R.K.; Olland, A.M. (2025). Structure of PAK1 in complex with compound 31. Protein Data Bank: 9d4y. |
CMCF-ID |
PDB Deposition |
Health |
| Forrester, T.J.B.; Kimber, M.S. (2025). human ClpP - Bortezomib - A192E / E196R. Protein Data Bank: 9dql. |
CMCF-ID |
PDB Deposition |
Health |
| Forrester, T.J.B.; Kimber, M.S. (2025). human ClpP - Apo - A192E / E196R. Protein Data Bank: 9dqk. |
CMCF-ID |
PDB Deposition |
Health |
| Frigon, L.; Pascal, J.M. (2025). PARP4 BRCT domain F39A mutant. Protein Data Bank: 9dfr. |
CMCF-BM |
PDB Deposition |
Health |