Publication Beamlines Strategic Pillar
Abdoli, Amirabbas; Yang, Zhihan; Odeh‐Ahmed, Abdullah; Bednova, Olga; Lemieux, Bruno et al. (2025). Probing the extent of importin‐α targeting of the TAF8 NLS by eliminating its cationic net‐charge. Protein Science 34(9) . 10.1002/pro.70272. [PDB: 9cl8, 9cle, 9clf, 9clg] CMCF-ID Agriculture
Ali, M.G.H.; Wahba, H.M.; Cyr, N.; Omichinski, J.G. (2024). Crystal structure of GABARAP in complex with the LIR of NSs4. Protein Data Bank: 8t2m. CMCF-BM Agriculture
Barghash, Marim M.; Mabanglo, Mark F.; Hoff, Samuel E.; Brozdnychenko, Dmytro; Wong, Keith S. et al. (2025). Small molecule dysregulation of ClpP activity via bidirectional allosteric pathways. Structure . 10.1016/j.str.2025.07.013. [PDB: 9mjp] CMCF-BM Agriculture
Chen, P.; Lamer, T.; Vederas, J.C.; Lemieux, M.J. (2025). Crystal structures of a cyanobacterial DAP epimerase bound to D,L-alpha-methyl DAP. Protein Data Bank: 9mrv. CMCF-BM Agriculture
Chen, P.; Lamer, T.; Vederas, J.C.; Lemieux, M.J. (2025). Crystal structures of a cyanobacterial DAP epimerase bound to either D,L-aziDAP or D,L-alpha-methyl DAP. Protein Data Bank: 9mro. CMCF-BM Agriculture
Delker, S.L.; Edwards, T.E.; Abendroth, J. (2025). Co-crystal structure of circularly permuted human taspase-1 bound to ligand SMDC1014689 1-(ethenesulfonyl)-4-{[3-fluoro-4-(trifluoromethoxy)phenyl]methyl}piperazine. Protein Data Bank: 9d03. CMCF-ID Agriculture
Delker, S.L.; Edwards, T.E.; Abendroth, J. (2025). Co-crystal structure of circularly permuted human taspase-1 bound to ligand SMDC1014883 (2R)-4-(ethenesulfonyl)-1-{[3-fluoro-4-(trifluoromethoxy)phenyl]methyl}-2-[(prop-2-yn-1-yloxy)methyl]piperazine. Protein Data Bank: 9d02. CMCF-ID Agriculture
Dementiev, A.A.; Michino, M.; Vendome, J.; Ginn, J.; Bryk, R. et al. (2024). Co-crystal structure of optimized analog TDI-13537 provided new insights into the potency determinants of the sulfonamide inhibitor series. Protein Data Bank: 8u0q. CMCF-ID Agriculture
Dodda, Leela S.; Campos, Sebastien; Ciccone, David; Carreiro, Samantha; Leit, Silvana et al. (2025). Knowledge and Structure-Based Drug Design of 15-PGDH Inhibitors. Journal of Medicinal Chemistry 68(17) , 18436-18462. 10.1021/acs.jmedchem.5c01231. [PDB: 9pfl] CMCF-BM Agriculture
Fraser, B.J.; Dong, A.; Ilyassov, O.; Kenney, T.; Li, Y.Y. et al. (2024). Human TMPRSS11D complexed with a disulfide-linked autoinhibitory DDDDK peptide. Protein Data Bank: 8vis. CMCF-ID Agriculture
Gunn, R.J.; Lawson, J.D.; Ivetac, A.; Ulaganathan, T.; Coulombe, R. et al. (2024). SOS2 crystal structure with fragment bound (compound 14). Protein Data Bank: 8t5m. CMCF-ID Agriculture
Gunn, R.J.; Lawson, J.D.; Ivetac, A.; Ulaganathan, T.; Coulombe, R. et al. (2024). SOS2 co-crystal structure with fragment bound (compound 12). Protein Data Bank: 8t5g. CMCF-ID Agriculture
Gunn, R.J.; Lawson, J.D.; Ivetac, A.; Ulaganathan, T.; Coulombe, R. et al. (2024). SOS2 crystal structure with fragment bound (compound 13). Protein Data Bank: 8t5r. CMCF-BM Agriculture
Hemmings, Mark; Zieliński, Michał; Golkar, Tolou; Blanchet, Jonathan; Pistofidis, Angelos et al. (2025). Enzyme-mediated aminoglycoside resistance without target mimicry. Communications Chemistry 8(1) . 10.1038/s42004-025-01666-0. [PDB: 9mgu] CMCF-ID Agriculture
Hemmings, M.; Blanchet, J.; Zielinski, M.; Golkar, T.; Berghuis, A.M. et al. (2025). Structure of aminoglycoside acetyltransferase AAC(3)-Ia in complex with CoA. Protein Data Bank: 9mgu. CMCF-ID Agriculture