Publication Beamlines Strategic Pillar
Zhao, Feipeng; Zhang, Shumin; Wang, Shuo; Reid, Joel W.; Xia, Wei et al. (2025). Anion sublattice design enables superionic conductivity in crystalline oxyhalides. Science 390(6769) , 199-204. 10.1126/science.adt9678. CMCF-BM, SXRMB Materials
Dodda, Leela S.; Campos, Sebastien; Ciccone, David; Carreiro, Samantha; Leit, Silvana et al. (2025). Knowledge and Structure-Based Drug Design of 15-PGDH Inhibitors. Journal of Medicinal Chemistry 68(17) , 18436-18462. 10.1021/acs.jmedchem.5c01231. [PDB: 9pfl] CMCF-BM Materials
Vázquez, M. C.; Reid, J. W.; Avila, Y.; González, M.; Sánchez, L. et al. (2024). Fe(L)2[M(CN)4] with L = 4-Ethyl Isonicotinate and M = Ni, Pd, Pt.─A Series of Hofmann-Type Frameworks with Spin Crossover: The Dominant Role of the Fe–NC Coordination Bond. Journal of Physical Chemistry C 128(22) , 9353-9363. 10.1021/acs.jpcc.4c01838. CMCF-BM Materials
Lin, Lirong; Tresp, David S.; Spasyuk, Denis M.; Lalancette, Roger A.; Prokopchuk, Demyan E. et al. (2024). Accessing Ni(0) to Ni(IV) via nickel–carbon–phosphorus bond reorganization. Chemical Communications 60(6) , 674-677. 10.1039/d3cc04687g. CMCF-BM Materials
Niu, Xun (2024). Valorization of wood bark towards value-added chemicals, structures, and bioproducts. Supervisor: Rojas, Orlando J.. British Columbia, Canada: University of British Columbia. https://open.library.ubc.ca/soa/cIRcle/collections/ubctheses/24/items/1.0445091?o=14. CMCF-BM Materials
Bekkering, Ezra T.; Yoo, Randy; Hailemariam, Sophia; Heide, Fabian; Ivanochko, Danton et al. (2025). Cryo-EM structure of endogenous Pfs230:Pfs48/45 complex with six antibodies reveals mechanisms of malaria transmission-blocking activity. Immunity . 10.1016/j.immuni.2025.09.014. [PDB: 9n7k] CMCF-ID Health
Hemmings, Mark; Zieliński, Michał; Golkar, Tolou; Blanchet, Jonathan; Pistofidis, Angelos et al. (2025). Enzyme-mediated aminoglycoside resistance without target mimicry. Communications Chemistry 8(1) . 10.1038/s42004-025-01666-0. [PDB: 9mgu] CMCF-ID Health
Abdoli, Amirabbas; Yang, Zhihan; Odeh‐Ahmed, Abdullah; Bednova, Olga; Lemieux, Bruno et al. (2025). Probing the extent of importin‐α targeting of the TAF8 NLS by eliminating its cationic net‐charge. Protein Science 34(9) . 10.1002/pro.70272. [PDB: 9cl8, 9cle, 9clf, 9clg] CMCF-ID Health
Bian, Zhiguo; Schmidt, Robert G.; Wilson, Noel S.; Duignan, David B.; Breinlinger, Eric et al. (2025). Discovery of Orally Efficacious Bridged Piperazines as smTNF Modulators. Journal of Medicinal Chemistry 68(14) , 14357-14383. 10.1021/acs.jmedchem.5c00323. [PDB: 9ojs, 9ok6] CMCF-ID Health
Weller, Caroline; Burnett, G. Leslie; Jiang, Lingyan; Chakraborty, Sujata; Zhang, Dongyu et al. (2025). A neomorphic protein interface catalyzes covalent inhibition of RAS G12D aspartic acid in tumors. Science 389(6758) . 10.1126/science.ads0239. [PDB: 9ct7, 9ct9, 9cta, 9ctb] CMCF-ID Health
Petzold, Georg; Gainza, Pablo; Annunziato, Stefano; Lamberto, Ilaria; Trenh, Peter et al. (2025). Mining the CRBN target space redefines rules for molecular glue–induced neosubstrate recognition. Science 389(6755) . 10.1126/science.adt6736. [PDB: 9nfr] CMCF-ID Health
Deschenes, Natalie M; Pérez-Vargas, Jimena; Zhong, Zoe; Thomas, Merrilee; Kenward, Calem et al. (2025). Functional and Structural Characterization of Treatment-Emergent Nirmatrelvir Resistance Mutations at Low Frequencies in the Main Protease (Mpro) Reveals a Unique Evolutionary Route for SARS-CoV-2 to Gain Resistance. Journal of Infectious Diseases . 10.1093/infdis/jiaf294. [PDB: 9pfh, 9pfi] CMCF-BM Health
Liu, Bin; Yao, Jiangchao; Haimowitz, Thomas; Benetatos, Christopher A.; Boyd, Steven A. et al. (2025). Discovery of VNRX-9945, a Potent, Broadly Active Capsid Assembly Modulator as a Clinical Candidate for the Treatment of Chronic Hepatitis B Virus Infection. ACS Medicinal Chemistry Letters . 10.1021/acsmedchemlett.5c00315. [PDB: 9n3h] CMCF-ID Health
Tong, Yunsong; Baker, Kenton A.; Chapman, Alex M.; Elsen, Nathaniel L.; Fowler, Faith et al. (2025). Validation, Key Pharmacophores, and X-ray Cocrystal Structures of Novel Biochemically and Cellularly Active WRN Inhibitors Derived from a DNA-Encoded Library Screen. Journal of Medicinal Chemistry . 10.1021/acs.jmedchem.4c03029. [PDB: 9og8] CMCF-ID Health
Knudson-Goerner, Emily; Boraston, Alisdair B. (2025). The structure of a family 168 glycoside hydrolase from the marine bacterium Muricauda eckloniae. Acta Crystallographica Section F:Structural Biology Communications 81(7) . 10.1107/s2053230x2500425x. [PDB: 9nhf] CMCF-ID Health