| Haines, Eric; Burke, Michael; Catterall, Rachel; De Jesus, Victor; Hidalgo, Daniel et al. (2026). The MEK–RAF molecular glue IK-595 has potent antitumor activity across RAS/MAPK pathway-altered cancers. Nature Cancer . 10.1038/s43018-025-01081-3. [PDB: 9ecu] |
CMCF-ID |
Peer-Reviewed Article |
Agriculture |
| Guo, Shuaiqi; Zahiri, Hossein; Stevens, Corey; Spaanderman, Daniel C.; Milroy, Lech-Gustav et al. (2021). Molecular basis for inhibition of adhesin-mediated bacterial-host interactions through a peptide-binding domain. Cell Reports 37(7) , 110002. 10.1016/j.celrep.2021.110002. [PDB: 6x5v, 6x5w] |
CMCF-ID |
Peer-Reviewed Article |
Agriculture |
| kimani, S.; Dong, A.; Li, Y.; Seitova, A.; Mamai, A. et al. (2026). Crystal structure of the human DCAF1 WDR domain in complex with OICR-40102. Protein Data Bank: 9y4q. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Qiu, Y. (2026). Crystal structure of BCMA in complex with CA10v2 Fab. Protein Data Bank: 9mqo. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Yang, A. (2026). Crystal structure of the inactive BRAF/MEK1 complex bound to IK-595. Protein Data Bank: 9ecu. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Shaffer, P.L. (2025). MENIN IN COMPLEX WITH JNJ-75276617 (Bleximenib). Protein Data Bank: 9z4x. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Kwon, Min Chul; Thuring, Jan Willem; Querolle, Olivier; Dai, Xuedong; Verhulst, Tinne et al. (2024). Preclinical efficacy of the potent, selective menin-KMT2A inhibitor JNJ-75276617 (bleximenib) in KMT2A- and NPM1-altered leukemias. Blood 144(11) , 1206-1220. 10.1182/blood.2023022480. [PDB: 9z4x] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Kimani, S.; Dong, A.; Li, Y.; Seitova, A.; Mamai, A. et al. (2025). Crystal structure of the human DCAF1 WDR domain in complex with OICR-41109. Protein Data Bank: 9yv4. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Kimani, Serah W.; Noureldin, Mahmoud; Wilson, Brian; Hoffer, Laurent; Green, Stuart R. et al. (2025). OICR-41103 as a chemical probe for the DCAF1 WD40 domain. Communications Biology 8(1) . 10.1038/s42003-025-08491-0. [PDB: 9yv4] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Wang, M.; Guo, S.; Kinrade, B.; Davies, P. (2025). Vibrio cholerae protein FrhA peptid-binding domain and adjacent split domain (S1127-F1439) in complex with peptide AGYTD X-ray crystallography structure. Protein Data Bank: 9ybq. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Wang, M.; Guo, S.; Kinrade, B.; Davies, P. (2025). Vibrio cholerae protein FrhA peptid-binding domain and adjacent split domain (S1127-F1439) in complex with peptide AGWTD X-ray crystallography structure. Protein Data Bank: 9y9w. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Wang, Mingyu; Du, Grace; Yongo‐Luwawa, Charity; Lu, Angelina; Kinrade, Brett et al. (2025). Peptide‐based ligand antagonists block a
Vibrio cholerae
adhesin. FEBS Letters . 10.1002/1873-3468.70231. [PDB: 9y9w, 9ybq] |
CMCF-ID |
Peer-Reviewed Article |
Health |
| Ereno-Orbea, J.; Sicard, T.; Julien, J.-P. (2025). Crystal structure of human CD22 Ig domains 1-3 in complex with modified sialoside 7-012. Protein Data Bank: 9ro7. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Paetzel, M.; Luo, C. (2025). Escherichia coli Signal Peptidase I Delta 2-76 P84A in complex with lipopeptide inhibitor. Protein Data Bank: 9nlo. |
CMCF-ID |
PDB Deposition |
Agriculture |
| Luo, Chuanyun; Paetzel, Mark (2025). Crystal structure of Escherichia coli type I signal peptidase P84A in complex with lipopeptide antibiotic arylomycin A2. Journal of Structural Biology 217(4) , 108260. 10.1016/j.jsb.2025.108260. [PDB: 9nlo] |
CMCF-ID |
Peer-Reviewed Article |
Health |